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TranscriptomicsComparative genomic hybridization by array of human de novo actue myeloid leukemia (p-AML) samples and normal samples
Therapy-related acute myeloid leukemia (t-AML) is a severe complication of the cytotoxic therapy used for primary cancer treatment. The outcome of these patients is poor compared to people who develop de novo acute myeloid leukemia (p-AML). Chromosome abnormalities in t-AML are partly dependent on t...
ORGANISM(S): Homo sapiens 
2011-05-18 | E-TABM-1014 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of human therapy related actue myeloid leukemia (t-AML) samples and normal samples
Therapy-related acute myeloid leukemia (t-AML) is a severe complication of the cytotoxic therapy used for primary cancer treatment. The outcome of these patients is poor compared to people who develop de novo acute myeloid leukemia (p-AML). Chromosome abnormalities in t-AML are partly dependent on t...
ORGANISM(S): Homo sapiens 
2011-06-08 | E-TABM-1015 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of a mother and daughter with a familial translocation t(2;6)(p25;p21) balanced in the mother and unbalanced in the daughter to determine breakpoint location and contribute to a map of haplotolerant genes
A 244 K genome-wide array based comparative genomic hybridization study was carried out in a familial translocation t(2;6)(p25;p21) balanced in the mother (SDM) and unbalanced in her daughter (SD). In the past, this translocation has allowed to localize the HLA multigene cluster to chromosome 6. Wit...
ORGANISM(S): Homo sapiens 
2008-12-31 | E-TABM-308 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of 121 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1133 | biostudies-arrayexpress
TranscriptomicsIGR_CREMEC_CGH_STYDY_LL
Patient-derived xenograft models are considered to represent the heterogeneity of human cancers and might be more relevant preclinical models to evaluate effective therapeutic agents. Our consortium joins efforts to extensively develop and characterize a new collection of patient-derived colorectal ...
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MTAB-992 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human lung adenocarcinoma in never smokers
CGH array in Lung Adenocarcinoma in Never Smokers
ORGANISM(S): Homo sapiens 
2010-12-31 | E-TABM-926 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse C57Bl and nude strain xenografts from adherent and stem cells
Astrocytes may give raise to glioma, the most frequent primitive CNS tumours. TGFa, an EGF family member, is trophic for both astrocytes and gliomas cells and is frequently over-expressed in the early stages of glioma progression. Although its sole deregulation is insufficient to lead to cancerous t...
ORGANISM(S): Mus musculus 
2009-07-06 | E-TABM-706 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of human Burkitts lymphoma samples
Additional chromosomal abnormalities are currently detected in Burkitt’s lymphoma. They play major roles in the progression of BL and in prognosis. The genes involved remain elusive. A whole-genome oligonucleotide array CGH analysis correlated with karyotype and FISH was performed in a set of 15 Bu...
ORGANISM(S): Homo sapiens 
2009-09-18 | E-TABM-703 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization by array of human intracranial childhood ependymomas at diagnosis and relapse
Goal of the experiment : Recurrence is a frequent phenomenon in intracranial childhood ependymomas. To understand this process, we investigated whether the gene expression profiling of matched ependymomas at diagnosis and at relapse could reveal key molecular events involved in tumor progression. To...
ORGANISM(S): Homo sapiens 
2011-06-20 | E-TABM-1023 | biostudies-arrayexpress
TranscriptomicsIGR_GLIOMA_STUDY_SP
Glioma study (gene expression and CGH): Brain tumours are the most common solid tumors in children and have the highest mortality rate of all solid pediatric tumours. Despite advances in multimodality therapy, children with high-grade gliomas invariably have an Overall Survival (OS) around 20% at 5 ...
ORGANISM(S): Homo sapiens 
2012-02-22 | E-TABM-1107 | biostudies-arrayexpress
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