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ProteomicsLabel-free quantitative proteomics analysis of Drosophila melanogaster lethal giant larvae mutants reveals potential therapeutic effects of melatonin
The present study is a pioneering investigation that has been carefully designed to study proteomic effects of specific cancer-related mutation using the lgl mutant of D. melanogaster that has not been well characterised thus far. Recent findings concerning the D. melanogaster cancer models suggest ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-05-10 | PXD033191 | Pride
Label-free quantitative proteomics Lethal giant larvae Circadian proteome Melatonin. Drosophila melanogaster 
ProteomicsInvestigation of the rhythmic changes in the proteome of different subtypes of pancreatic ductal adenocarcinoma
At present, there is no reliable biomarker for the diagnosis of pancreatic ductal adenocarcinoma (PDAC). Due to this, together with the asymptomatic nature of the cancer, PDAC is often diagnosed at an advanced stage with an abysmal 5-year survival rate. Hence, a reliable biomarker for the timely dia...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD054693 | Pride
Circadian rhythm Label-free quantitative proteomics Mass spectrometry Pdac Biomarker 
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