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TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors DASL Cancer Panel
HER2-positive and HER2-negative samples are compared within this DASL Cancer Panel Platform Two-class comparison
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25231 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors Whole Genome DASL
HER2-positive and HER2-negative samples are compared within this Whole Genome Platform Two-class comparison
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25233 | biostudies-arrayexpress
TranscriptomicsExperimental identification of miR-378-3p targets by overexpression and silencing in murine NIH-3T3 fibroblasts
MicroRNAs (miRNAs) are short noncoding RNA molecules regulating the expression of mRNAs. Target identification of miRNAs is computationally difficult due to the relatively low homology between miRNAs and their targets. We provide data here utilizing an experimental approach to identify targets of mm...
ORGANISM(S): Mus musculus 
2012-08-07 | E-GEOD-34873 | biostudies-arrayexpress
TranscriptomicsAlternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct
Macrophages adopt an alternatively activated phenotype (AAM) when activated by IL-4. While these AAMs can be derived from local proliferation of resident tissue macrophages or recruited inflammatory monocytes, it is not known whether these different AAMs are phenotypically and functionally distinct....
ORGANISM(S): Mus musculus 
2014-02-05 | E-GEOD-54679 | biostudies-arrayexpress
TranscriptomicsSIRT1 affects DNA methylation of polycomb group protein target genes (PCGTs), a hotspot of the epigenetic shift observed in ageing
Beneficial effects of SIRT1 on healthspan are likely to be pleiotropic and may include effects on DNA methylation. We demonstrated recently that manipulating SIRT1 in human cells affected DNA methylation of a panel of test genes, and that genes with expression modified by dietary restriction corresp...
ORGANISM(S): Homo sapiens 
2014-03-31 | E-GEOD-53569 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Dop1R2 RNAi in Drosophila melanogaster
The process of metamorphosis relies on choreography of temporal and spatial cues that mediate, in which inappropriate activation of many of these genes results in growth defects, developmental delay and death. Using RNA interference, we have unraveled an essential role for the insect specific dopam...
ORGANISM(S): Drosophila melanogaster 
2015-09-01 | E-GEOD-66496 | biostudies-arrayexpress
TranscriptomicsExpression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors
This SuperSeries is composed of the following subset Series: GSE25231: Expression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors DASL Cancer Panel GSE25233: Expression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors Whole Genome DASL Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-25234 | biostudies-arrayexpress
UnknownPhysical activity patterns and clusters in 1001 patients with COPD.
Not available
S-EPMC5720232 | biostudies-literature
TranscriptomicsCoordination in the transcriptome and proteome of the diatom Thalassiosira pseudonana reveals a diverse phosphorus stress response
Phosphorus (P) is a critical driver of phytoplankton growth and ecosystem structure and function in the ocean. Diatoms are an abundant and widespread functional group of phytoplankton that are responsible for significant amounts of primary production in the ocean, however there has not been a compre...
ORGANISM(S): Thalassiosira pseudonana CCMP1335 
2013-08-03 | E-GEOD-28134 | biostudies-arrayexpress
TranscriptomicsBcl11a (Ctip1) controls migration of cortical projection neurons through regulation of Sema3c
During neocortical development, neurons undergo polarization, oriented migration, and layer type-specific differentiation. The transcriptional programs underlying these processes are not completely understood. Here we show that the transcription factor Bcl11a regulates polarity and migration of uppe...
ORGANISM(S): Mus musculus 
2015-06-17 | E-GEOD-52827 | biostudies-arrayexpress
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