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ModelsJensen2020 - Streptococcus oralis (iCJ415)
We have presented FROG and miniFROG reports for the first genome-scale model, iCJ415, for Streptococcus oralis SK141. The model can be found in the Supplementary Material of the publication by Jensen et al, 2020 cited here.
2024-10-15 | BIOMD0000001086 | BioModels
FROG 
ProteomicsMolecular basis of polyadenylated RNA fate determination in the nucleus
Eukaryotic genomes generate a plethora of polyadenylated (pA+) RNAs1,2, that are packaged into ribonucleoprotein particles (RNPs). To ensure faithful gene expression, functional pA+ RNPs, including protein-coding RNPs, are exported to the cytoplasm, while transcripts within non-functional pA+ RNPs a...
ORGANISM(S): Homo sapiens (Human) 
2026-06-19 | PXD076297 | Pride
TranscriptomicsZbtb20-mediated repression of genes in developing CA1 pyramidal neurons
The transcriptional repressor Zbtb20 is essential for specification of hippocampal CA1 pyramidal neurons. Moreover, ectopic expression of Zbtb20 is sufficient to transform subicular and retrosplenial areas of D6/Zbtb20S mice to CA1. We used microarrays to identify genes that are repressed by Zbtb20 ...
ORGANISM(S): Mus musculus 
2014-04-11 | E-GEOD-38837 | biostudies-arrayexpress
ProteomicsIdentification of pspA-3’UTR-regulated proteins by quantitative proteomics
RNA-mediated control of virulence gene expression is widespread among pathogenic bacteria. However, in some major human pathogens such as Streptococcus pneumoniae, its role remains poorly understood. In this study we identify a regulatory function for the 3’-untranslated region (3’UTR) of the mRNA e...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2026-05-27 | PXD040356 | Pride
Lc-msms Streptococcus pneumoniae Tmt10plex Pathogenic bacteria Regulatory rnas 
MetabolomicsPlasmid-encoded toxin defence mediates mutualistic microbial interactions

Gut environments harbour dense microbial ecosystems in which plasmids are widely distributed. Plasmids facilitate the exchange of genetic material among microorganisms while enabling the transfer of a diverse array of accessory functions. However, their precise impact on microbial community compo...

2023-08-10 | MTBLS7248 | MetaboLights
TranscriptomicsRNA-seq of murine small intestinal organoids treated with type I PRMT inhibitor MS023 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 5µM inhibitor MS023 (PubChem CID 92136227), which targets type I protein arginine methyltransferases Prmt1, Prmt3, Prmt4, Prmt6, Prmt8. Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), medi...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9291 | biostudies-arrayexpress
TranscriptomicsRNA-seq of murine small intestinal organoids treated with Ep300/Crebbp inhibitor I-CBP112 against untreated controls
Murine small intestinal organoids were cultured in the presence or absence of 3µM inhibitor I-CBP112 (PubChem CID 90488984), which targets E1A Binding Protein P300 (Ep300) and Creb-binding protein (Crebbp, Cbp). Organoids were grown in culture media containing EGF, Noggin and R-spondin (ENR), media ...
ORGANISM(S): Mus musculus 
2020-12-16 | E-MTAB-9290 | biostudies-arrayexpress
UnknownA semi-automated intestinal organoid screening method demonstrates epigenetic control of epithelial maturation
Not available
ORGANISM(S): Mus musculus 
S-BSST447 | biostudies-other
UnknownProteolytic profiling of human plasma reveals an immunoactive complement C3 fragment
Not available
S-SCDT-10_1038-S44318-025-00598-8 | biostudies-other
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