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ProteomicsA Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients
State-of-the-art proteomics-grade mass spectrometers can measure peptide precursors and their fragments with ppm mass accuracy at sequencing speeds of tens of peptides per second with attomolar sensitivity. Here we describe a compact and robust quadrupole-orbitrap mass spectrometer equipped with a f...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2020-02-17 | PXD016662 | Pride
Faims Dia Tmt Bottom-up shotgun proteomics Phosphoproteomics Orbitrap Dda 
TranscriptomicsExpression data from Pseudomonas aeruginosa (wild type and lasRrhlR mutant strains) exposed to human neutrophils
In the present in vitro study, interactions between P. aeruginosa (sessile biofilms as well as planktonic cells) and PMNs were analyzed by means of DNA microarray based transcriptomics. We found that the P. aeruginosa wild type biofilms, in contrast to planktonic cultures and quorum sensing (QS) def...
ORGANISM(S): Pseudomonas aeruginosa 
2009-08-04 | E-GEOD-6769 | biostudies-arrayexpress
TranscriptomicsDeep profiling of the novel intermediate-size noncoding RNAs in intraerythrocytic Plasmodium falciparum
Intermediate-size noncoding RNAs (is-ncRNAs) have been shown to play important regulatory roles in the development of several eukaryotic organisms. However, they have not been thoroughly explored in Plasmodium falciparum, which is the most virulent malaria parasite infecting human being. By using Il...
ORGANISM(S): Plasmodium falciparum 
2014-03-30 | E-GEOD-45172 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of different developmental stages of Plasmodium falciparum to identify expression of non-coding RNAs
In summary, we present a systematic in silico screen for the conserved non-coding RNA structures by comparing the P. falciparum genome with seven other malaria species and describe 668 candidate RNA secondary structures. By combining microarray and northern data, we provide evidence for expression o...
ORGANISM(S): Plasmodium falciparum 
2007-08-23 | E-SGRP-8 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of P. falciparum parasites from human placenta or culture
Comparison of P. falciparum parasites from human placental vs culture parasites
ORGANISM(S): Plasmodium falciparum 
2007-10-01 | E-MEXP-1087 | biostudies-arrayexpress
ProteomicsZAKb is a cellular compression sensor that mediates hypertrophic signaling in skeletal muscle
Mechanosensing is required for the senses of touch and hearing, and impacts on cellular processes such as cell differentiation, migration, invasion and tissue homeostasis. Mechanical inputs give rise to p38- and JNK-signaling, which mediates adaptive physiological responses in various tissues. In mu...
ORGANISM(S): Mus musculus (Mouse) 
2022-05-31 | PXD028548 | Pride
Zak Phosphoproteomics Mouse. muscle 
TranscriptomicsMolecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins
The human malaria parasite Plasmodium falciparum employs intricate post-transcriptional regulatory mechanisms in different stages of its life cycle. Despite the importance of post-transcriptional regulation, key elements of these processes, namely RNA binding proteins (RBPs), are poorly characterize...
ORGANISM(S): Plasmodium falciparum 
2014-10-23 | E-GEOD-56329 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of FCR3 P. falciparum parasites phenotypicaly selected for adhesion on CSA or CD36
Comparison of FCR3 P. falciparum parasites phenotypicaly selected for adhesion on CSA or CD36.
ORGANISM(S): Plasmodium falciparum 
2005-12-31 | E-MEXP-319 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type, Pfsir2A knock-out and Pfsir2B knock-out Plasmodium falciparum intra-erythrocytic stages
Pfsir2A and Pfsir2B KOs expression profiling in intra-erythrocytic stages
ORGANISM(S): Plasmodium falciparum 
2008-05-01 | E-TABM-438 | biostudies-arrayexpress
TranscriptomicsLong non-coding RNAs detected in Plasmodium falciparum malaria using high-resolution DNA tiling microarray technology.
Survey of transcriptional activity across 22.6% of the P. falciparum strain 3D7 genome. 872 protein coding genes and 60 putative P. falciparum lncRNAs identified under developmental regulation during the parasite's pathogenic human blood stage. Total RNA was isolated from synchronous in vitro parasi...
ORGANISM(S): Plasmodium falciparum 3D7 
2011-03-16 | E-GEOD-27937 | biostudies-arrayexpress
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