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TranscriptomicsGene expression programs of histologically distinct stages of prostate carcinogenesis in Nkx3.1; Pten mutant mice
Key histological and growth progression characteristics of human prostate cancer are phenocopied in mouse models that have been subjected to androgen level depletion and engineered for hemizygosity of candidate prostate cancer tumor suppressor genes Nkx3.1 and Pten. To characterize their relative tr...
ORGANISM(S): Mus musculus 
2009-10-31 | E-GEOD-15943 | biostudies-arrayexpress
TranscriptomicsMEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors, despite transcriptional feedback onto ERK.
Neurofibromatosis Type 1 (NF1) patients develop benign neurofibromas and malignant peripheral nerve sheath tumors (MPNST). These incurable peripheral nerve tumors result from loss of NF1 tumor suppressor gene function, causing hyperactive Ras signaling. Activated Ras controls numerous downstream eff...
ORGANISM(S): Mus musculus 
2012-12-28 | E-GEOD-41747 | biostudies-arrayexpress
UnknownEndothelial cell density to predict endothelial graft failure after penetrating keratoplasty.
Not available
S-EPMC2950322 | biostudies-literature
UnknownFactors associated with corneal graft survival in the cornea donor study.
Not available
S-EPMC4394864 | biostudies-literature
UnknownAssociations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
Not available
S-EPMC4469461 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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