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ProteomicsArginine and lysine methylproteomes of Giardia duodenalis
Methylation is a common post-translational modification of lysine and arginine in eukaryotic proteins. To date, these methylomes are best characterised in model organisms and higher eukaryotes. Herein, we integrated bioinformatics, proteomics and high-content drug-screening to comprehensively explor...
ORGANISM(S): Giardia lamblia ATCC 50803 
2020-08-07 | PXD016813 | Pride
Methylation Arginine methylation Ptm Giardia Lysine methylation 
ProteomicsProtein posttranslational modifications of Giardia histones
Diarrheal disease caused by Giardia duodenalis is highly prevalent, totalling over 200 million cases globally each year. The processes which drive parasite virulence, host immune evasion and transmission involve coordinated gene expression, which are likely post-transcriptionally regulated. Epigenet...
ORGANISM(S): Giardia intestinalis assemblage A 
2025-08-28 | PXD019949 | Pride
Methylation Giardia Histones Chromatin Acetylation Phosphorylation 
ProteomicsEncystation deep proteome of Giardia duodenalis
Background: Cyst formation in parasitic protist Giardia duodenalis is critical to its transmission. Proteomic data is essential for the system-level understanding of the molecular mechanisms managing stage transition from a flagellated, binucleate trophozoite to a tetra-nucleate cyst. The current en...
ORGANISM(S): Giardia lamblia ATCC 50803 
2023-02-08 | PXD016863 | Pride
Proteomics Deep proteome Giardia Encystation 
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