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Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights

BACKGROUND: Cryopyrin-Associated Periodic Syndrome (CAPS) is an autoinflammatory condition consequence of monoallelic variants in the NLRP3 gene that exacerbate IL-1β production. These variants are gain-of-function, but the exact regulatory mechanism of the NLRP3 CAPS-inflammasom...

2024-01-09 | MTBLS7872 | MetaboLights
Identification of PHB Granule-associated Proteins in B. diazoefficiens and a phaR mutant, both cultured under microoxic conditions (0.5% O2) in Götz minimal medium supplemented with mannitol.
ORGANISM(S): Bradyrhizobium japonicum USDA 110 Bacteria 
2024-05-21 | PXD047962 | Pride
Bradyrhizobium diazoefficiens can live inside soybean root nodules and in free-living conditions. In both states, when oxygen levels decrease, cells adjust their protein pools by gene transcription modulation. PhaR encodes a transcription factor annotated as PHA (polyhydroxyalkanoate) accumulation r...
ORGANISM(S): Bradyrhizobium japonicum USDA 110 Bacteria 
2024-05-22 | PXD047760 | Pride
The protein profiles of both the dnaK deletion mutant and the wild-type strain were analyzed using proteomic analysis. The dnaK deletion mutant was analyzed three times and the wild-type strain was also analyzed three times.
ORGANISM(S): Cronobacter Sakazakii 
2023-02-16 | PXD040215 |
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