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TranscriptomicsThe ThbZIP1 can be regulated by an ABF Transcription Factor and sensitivity to ABA treatment
In the current report, we report that ThbZIP1 is a direct target gene of the ThABF1 transcription factor. There are three ABRE motifs in the promoter of ThbZIP1, Yeast one-hybrid (Y1H) assays showed that a ABF protein, ThABF1, specifically binds to the ABRE motifs. The interaction between ThABF1 and...
ORGANISM(S): Arabidopsis thaliana 
2014-11-01 | E-GEOD-62888 | biostudies-arrayexpress
ProteomicsLC-MS/MS identification of BMAL1 interaction proteins
Advances in circadian research revealed an intricate relationship between aging and circadian rhythms. However, whether and how the circadian machinery contribute to stem cell aging, especially in primates, remains poorly understood. In this study, we investigated the role of BMAL1, the only non-red...
ORGANISM(S): Homo sapiens (Human) 
2022-03-18 | PXD030570 | Pride
Bmal1 aging 
UnknownWidespread long-range cis-regulatory elements in the maize genome.
Not available
S-EPMC6904520 | biostudies-literature
ProteomicsClinical characterization and proteomic profiling of lean nonalcoholic fatty liver disease
To investigate the proteomic features in lean subjects with NAFLD, and to identify possible plasma proteins that provide potential application for diagnosing of NAFLD in lean individuals. Participants with or without NAFLD were divided into an overweight NAFLD group, an overweight control group, a l...
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035514 |
ProteomicsCCL20/CXCL5 regulates the stemness of anaplastic thyroid cancer stem cells via NF-kB pathway
The mechanism of CCL20/CXCL5 regulating anaplastic thyroid cancer cancer stem cells to promote the progression of thyroid cancer
ORGANISM(S): Homo Sapiens 
2023-11-13 | PXD046889 |
ProteomicsA brain signaling framework for stress-induced depression and ketamine treatment elucidated by phosphoproteomics
Depression is a common affective disorder characterized by significant and persistent low mood.Ketamine, an N-methyl-D-aspartate receptor (NMDAR) antagonist, is reported to have a rapid and durable antidepressant effect.
ORGANISM(S): Mus Musculus 
2019-11-18 | PXD016302 |
ProteomicsTumor necrosis factor α-induced protein 1 as a novel tumor suppressor through selective downregulation of CSNK2B blocks Nuclear Factor-κB activation in hepatocellular carcinoma
Background: Tumor necrosis factor α-induced protein 1 (TNFAIP1) is frequently downregulated in cancer cell lines and promotes cancer cell apoptosis. However, its role, clinical significance and molecular mechanisms in hepatocellular carcinoma (HCC) are unknown. Methods: The expression of TNFAIP1 in...
ORGANISM(S): Homo Sapiens 
2019-11-19 | PXD016329 |
ProteomicsProteogenomic analysis of chemo-refractory high grade serous ovarian cancer
To improve our understanding of the molecular basis of chemo-refractory high grade serous ovarian cancers (HGSOCs), we characterized the proteogenomic landscape of 242 (refractory and sensitive) HGSOCs, representing one discovery and two independent validation cohorts (spanning four academic centers...
ORGANISM(S): Homo Sapiens 
2023-09-18 | PXD040742 | panorama
ProteomicsMouse Testis IP-MS Analysis of TEX44 Interacting Proteins
Through whole-exome sequencing of 800 patients with asthenozoospermia, we identified biallelic TEX44 variants in six individuals, all of whom exhibited defective mitochondrial sheath assembly and impaired sperm motility. Using Tex44 knockout mice, we demonstrated that TEX44 interacts with carnitine ...
ORGANISM(S): Mus Musculus 
2025-02-20 | PXD060989 |
ProteomicsCPTAC CCRCC Discovery Study - DIA Proteome
This is a supplementary study to the CPTAC CCRCC Discovery Study - Proteome. Unlabeled, digested peptide material from individual tissue samples (ccRCC and NAT) was spiked with index Retention Time (iRT) peptides (Biognosys) and subjected to data-independent acquisition (DIA) analysis. Kidney cance...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-04 | MSV000093041 | MassIVE
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