Jia Jia J - OmicsDI

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UNIPROT ID/AC

Q8N339 (2)
Q8IZ21 (2)
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Q15369 (2)

ENSEMBL ID

ENSG00000170477 (2)
ENSG00000247315 (1)

CHEBI ID

CHEBI:30769 (20)
CHEBI:17568 (19)
CHEBI:17368 (19)
CHEBI:17154 (19)
CHEBI:16750 (18)
CHEBI:16704 (18)
CHEBI:16708 (18)
CHEBI:15756 (18)
CHEBI:16857 (17)
CHEBI:17895 (17)
CHEBI:16919 (17)
CHEBI:7916 (17)
CHEBI:17596 (17)
CHEBI:16335 (17)
CHEBI:17821 (16)
CHEBI:17405 (16)
CHEBI:17750 (16)
CHEBI:15741 (16)
CHEBI:17748 (15)
CHEBI:27823 (15)
CHEBI:16828 (15)
CHEBI:16737 (15)
CHEBI:16467 (15)
CHEBI:15354 (15)
CHEBI:17015 (15)
CHEBI:15891 (15)
CHEBI:16865 (15)
CHEBI:30746 (14)
CHEBI:17752 (14)
CHEBI:16359 (14)

Metabolite Name

Uracil (14)
Xanthine (14)
Hypoxanthine (12)
L-Tyrosine (12)
Uric acid (12)
Guanosine (12)
Inosine (12)
L-Proline (12)
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L-Methionine (10)
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L-Tryptophan (10)
Linoleic acid (10)
Creatinine (10)
L-Valine (10)
4-Pyridoxic acid (9)
Riboflavin (9)
Azelaic acid (9)
L-Alanine (9)
L-Arginine (9)
L-Serine (9)
Cytosine (9)

First Public Date

2014 (4)
2021 (1)

Modelling Approach

Ordinary differential equation model (3)

Lab affiliation

Tsinghua University, China (4)
Children's Hospital of Nanjing Medical University (3)
Cancer Research UK Cambridge Institute, University of Cambridge (3)
Max Delbrück Center for Molecular Medicine (3)
Northwest University (3)
Central South University (2)
Tianjin Medical University General Hospital (2)
Hebei Medical University (2)
College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, Hubei, P. R. China. (2)
Center for Stem Cell Biology and Tissue Engineering, Key Laboratory for Stem Cells and Tissue Engineering, Ministry of Education, Sun Yat-sen University, Guangzhou, Guangdong, China. (2)
University of Science and Technology of China (2)
State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, China (2)
State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, China. (2)
Department of Urology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, P. R. China (2)
Peking University (2)
Zhejiang University (2)
Laboratory of Cell Growth Control by Nutrients, Inserm U1151, Necker Enfants Malades Institute (INEM), Faculté de Médecine Paris Descartes, Leriche Building 14 Rue Maria Helena Vieira da Silva Paris 75014 France (1)
., Department of Laboratory Medicine, Medical University of Vienna, 18-20 Währinger Gürtel, 1090 Vienna, Austria (1)
Department of Immunology, Tianjin Medical University, Tianjin, China (1)
School of Pharmaceutical Science and Technology, Tianjin University (1)
Goethe University Frankfurt, University Hospital, Clinic of Neurology, Exp. Neurology, Heinrich Hoffmann Str. 7, 60590 Frankfurt am Main, Germany (1)
College of plant protection, Southwest University, China (1)
The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China (1)
Max-Planck-Institute for Multidisciplinary Sciences Bioanalytical Mass Spectrometry Group University Medical Center Goettingen Bioanalytics (1)
Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Germany (1)
Collaborative Innovation Center of Henan Grain Crops and State Key Laboratory of Wheat and Maize Crop Science/College of Agronomy, Henan Agricultural University, Zhengzhou, China 450001 (1)
Chinese Academy of Sciences University,Center for Excellence in Molecular & Cellular Sciences, State Key Laboratory of Molecular Biology, Institute of Biochemistry & Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Rd., Shanghai, China 200031 (1)
No.2699, Gaoke West Road, Pudong New Area, Shanghai (1)
Medizinisches Proteom-Center Ruhr-Universität Bochum 44801 Bochum Germany (1)
MOE Key Laboratory of Bioinformatics, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China (1)

IsPrivate

False (3)

Study type

Transcription profiling by array (70)
RNA-seq of coding RNA (20)
ChIP-seq (9)
RNA-seq of non coding RNA (7)
Methylation profiling by high throughput sequencing (6)
Comparative genomic hybridization by array (4)
Methylation profiling by array (4)
Unknown experiment type (2)
ChIP-chip by tiling array (2)
High-throughput sequencing (1)
Transcription profiling by tiling array (1)
RNAi profiling by array (1)
Transcription profiling by RT-PCR (1)
Other (1)

Release Date

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Subtype-specific peripheral blood gene expression profiles in recent onset JIA

Objective: A multi-center study of recent onset juvenile idiopathic arthritis (JIA) subjects prior to treatment with DMARDS or biologics was undertaken to identify peripheral blood gene expression differences between JIA subclasses and controls. Methods: PBMC from 59 healthy children and 136 JIA ...

ORGANISM(S): Homo sapiens

2009-06-30 | E-GEOD-13501 | biostudies-arrayexpress

RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients

Through RNA sequencing of CD4+ Tmemory/effector cells derived from the synovium of JIA patients and healthy controls, we analyzed the JIA gene expression signature. Treatment of autoinflammatory site-derived patient T cells with the BET-inhibitor JQ1 inhibited immune-related super-enhancers and pref...

ORGANISM(S): Homo sapiens

2015-09-15 | E-GEOD-71595 | biostudies-arrayexpress

Epigenetic profiling of Juvenile Idiopathic Arthritits (JIA) patients

With H3K27ac chromatin immunoprecipitation we identified a disease-specific, inflammation-associated, (super-)enhancer signature in JIA patient synovial fluid-derived CD4+ memory/effector T cells. This signature consists of unique pathogenesis-associated epigenetic changes which extend beyond genera...

ORGANISM(S): Homo sapiens

2015-09-15 | E-GEOD-71596 | biostudies-arrayexpress

Transcription profiling of peripheral blood samples from juvenile idiopathic arthritis (JIA) patients pre and post methotrexate therapy. Expression data from SPARKS CHARMS JIA cohort

Gene expression on peripheral blood mononuclear cells (PBMC) from SPARKS CHARMS juvenile idiopathic arthritis (JIA) cohort pre and post methotrexate therapy. This is the first study to our knowledge, to evaluate gene expression profiles in children with JIA before and after MTX, and to analyze genet...

ORGANISM(S): Homo sapiens

2010-09-27 | E-GEOD-23687 | biostudies-arrayexpress

Remission in Polyarticular Juvenile Idiopathic Arthritis

Identify biomarkers to predict response to therapy in polyarticular juvenile idiopathic arthritis (JIA) using gene expression microarrays. 42 samples from 13 controls, 14 active patients, 9 patients in clinical remission with medication (CRM), and 6 patients in clinical remission without medication ...

ORGANISM(S): Homo sapiens

2009-04-13 | E-GEOD-15645 | biostudies-arrayexpress

Burden of comorbid conditions in children and young people with juvenile idiopathic arthritis: a collaborative analysis of 3 JIA registries.

Not available

S-EPMC9157174 | biostudies-literature

The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource.

Not available

S-EPMC10339614 | biostudies-literature

Trajectories of disease courses in the inception cohort of newly diagnosed patients with JIA (ICON-JIA): the potential of serum biomarkers at baseline.

Not available

S-EPMC8088653 | biostudies-literature

Expression data from Fibroblast-like Synoviocytes (FLS) isolated from patients with Juvenile Idiopathic Arthritis (JIA) - compares untreated FLS to FLS exposed to conditioned media from Chondrocytes (Ch)