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MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
MetabolomicsUltraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model
This study aims to identify biomarkers for evaluating the therapeutic efficacy of mesalazine on ulcerative colitis by metabolomics and lipidomics. A dextran sulfate sodium-induced mouse model was used. The disease status was assessed by a disease activity index, the TNF-α level of colon was measured...
2022-10-24 | MTBLS2111 | MetaboLights
UnknownCell Cycle Genes Are Potential Diagnostic and Prognostic Biomarkers in Hepatocellular Carcinoma.
Not available
S-EPMC7298261 | biostudies-literature
ProteomicsLabel-free Quantitative Proteomics Identifies Novel Plasma Biomarkers for Distinguishing Pulmonary Tuberculosis and Latent Infection
Lack of effective differential diagnostic methods between active tuberculosis (TB) and latent infection (LTBI) is still an obstacle for TB control. Furthermore, the molecular mechanism behind the progression from LTBI to active TB has been not elucidated until now. Therefore, we performed label-free...
ORGANISM(S): Homo Sapiens 
2024-09-20 | PXD056149 |
ProteomicsProteome and lipidome of Urine-derived Exosomes in Mycobacterium tuberculosis Infected Patients
This study confirmed the aberrant lipids and protein spectrum in exosomes of Mtb infected individuals, uncovered novel potential lipid biomarkers for TB/LTBI diagnosis and revealed integral role of exosomal lipid-raft-dependent biological processes in TB pathogenesis.
ORGANISM(S): Homo Sapiens 
2024-03-04 | PXD050345 |
ProteomicsTargets Identification of NPB by the combined use of DARTS technology and proteomics
We found that the stability of OorD protein increased with the combination of DARTS technology and mass spectrometry identification.This result suggests that OorD may be a target of NPB.
ORGANISM(S): Helicobacter Pylori G27 
2024-11-26 | PXD058270 |
UnknownContinuous positive airway pressure (CPAP) vs noninvasive positive pressure ventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: protocol for an assessor-blinded, multicenter, randomized controlled trial.
Not available
S-EPMC6659219 | biostudies-literature
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