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MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
MetabolomicsTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
ProteomicsComprehensive mass spectrometry strategy for developing proteomic biomarkers of intracranial aneurysms
This study deals with discovering biomarkers for the diagnosis of intracranial aneurysm
ORGANISM(S): Oryctolagus Cuniculus Homo Sapiens 
2021-07-05 | PXD027116 |
ProteomicsCirculating proteomic panels for risk stratification of intracranial aneurysm and its rupture
This study deals with discovering biomarkers for the diagnosis of intracranial aneurysm
ORGANISM(S): Homo Sapiens 
PXD024615 |
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