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UnknownThe Rbm38-p63 feedback loop is critical for tumor suppression and longevity.
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S-EPMC5970038 | biostudies-literature
ProteomicsNovel Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multi-Omics Analysis
Intrahepatic cholangiocarcinoma (ICC) is a relatively rare but highly aggressive tumour type that responds poorly to chemotherapy and immunotherapy. Comprehensive molecular characterization of ICC is essential for the development of novel therapeutics. Here, we constructed two independent cohorts fr...
ORGANISM(S): Homo Sapiens 
2022-04-13 | PXD033206 |
ProteomicsOligomerization of PRMT1 Regulated RNA-Binding Protein Cascade Promotes Pancreatic Ductal Adenocarcinoma
PRMT1 is the predominant type I protein arginine methyltransferase responsible for generating monomethylarginine and asymmetric dimethylarginine (MMA and ADMA) in various protein substrates. It regulates numerous biological processes, including RNA metabolism, mRNA splicing, DNA damage repair, and c...
ORGANISM(S): Homo Sapiens 
2025-03-12 | PXD061743 |
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