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TranscriptomicsGene expression variation in Y-substitution lines in different genetic backgrounds of Drosophila melanogaster
We studied Y chromosomes from two geographically diverse populations of Drosophila melanogaster, and show that these Y chromosomes differentially modify the expression of hundreds of autosomal and X-linked genes. Genes showing Y-linked regulatory variation also show an association with immune respon...
ORGANISM(S): Drosophila melanogaster 
2010-05-08 | E-GEOD-21587 | biostudies-arrayexpress
MetabolomicsCD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12<sup>+</sup> microglia transformation.
CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
UnknownAntibody-Mediated Inhibition of HLA/LILR Interactions Breaks Innate Immune Tolerance and Induces Antitumor Immunity.
Not available
S-EPMC12560147 | biostudies-literature
UnknownEfficacy and safety of vonoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy for patients with <i>Helicobacter pylori</i> infection: a meta-analysis.
Not available
S-EPMC11962034 | biostudies-literature
UnknownBrain lipidomics and neurodevelopmental outcomes in intrauterine growth restricted piglets fed dairy or vegetable fat diets.
Not available
S-EPMC8885751 | biostudies-literature
UnknownEfficacy and safety of a basal insulin + 2-3 oral antihyperglycaemic drugs regimen versus a twice-daily premixed insulin + metformin regimen after short-term intensive insulin therapy in individuals with type 2 diabetes: The multicentre, open-label, randomized controlled BEYOND-V trial.
Not available
S-EPMC9543477 | biostudies-literature
UnknownCausality of genetically determined gut microbiota on lung cancer: a Mendelian randomization study.
Not available
S-EPMC12268612 | biostudies-literature
UnknownThe use of targeted exome sequencing in genetic diagnosis of young patients with severe hypercholesterolemia.
Not available
S-EPMC5103295 | biostudies-literature
UnknownPiperlongumine conquers temozolomide chemoradiotherapy resistance to achieve immune cure in refractory glioblastoma via boosting oxidative stress-inflamation-CD8+-T cell immunity.
Not available
S-EPMC10170830 | biostudies-literature
UnknownWorldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults.
Not available
S-EPMC5735219 | biostudies-literature
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