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Genomic studies of lung adenocarcinoma (LUAD) have advanced understanding of the disease’s biology and accelerated targeted therapy. However, proteomic characteristics of LUAD remain poorly understood. We carried out comprehensive proteomic analysis of 103 cases of LUAD in Chinese patients. Integrat...
ORGANISM(S): Homo Sapiens 
AMPK is a conservative energy sensor that plays roles in diverse cellular processes via direct phosphorylation on various substrates. Emerging studies have demonstrated the regulatory roles of AMPK in DNA damages, but the underlying mechesiams remains to be fully understood. Our studies provided a s...
ORGANISM(S): Mus Musculus 
2022-12-29 | PXD039113 |
KRAS mutant cancers, which feature the activation of multiple phosphorylation signaling pathways, remain a major challenge for cancer therapy. This study provides a landscape of the proteomics and phosphoproteomics of KRAS mutant cancers by analyzing different KRAS mutant human cancer cell lines acr...
ORGANISM(S): Homo Sapiens 
2021-06-23 | PXD026892 |
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