Sort   by:  
 Page size 
MetabolomicsHyocholic acid species as novel biomarkers for metabolic disorders
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
TranscriptomicsMouse Marginal Zone B-cell with/without Tfh RNASeq data analysis
Mouse Marginal Zone B-cell with/without Tfh
ORGANISM(S): Mus musculus 
2024-01-24 | E-MTAB-11677 | biostudies-arrayexpress
MetabolomicsTheabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
UnknownComparative optical genome analysis of two pangolin species: Manis pentadactyla and Manis javanica.
Not available
S-EPMC6082621 | biostudies-literature
GenomicsGenome-wide chromatin-immunoprecipitation studies of purified SAN cells reveals critical direct targets of ISL1 and suggests potential co-factor families for ISL1 action in SAN cells
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
2015-07-23 | E-GEOD-68974 | biostudies-arrayexpress
ProteomicsLncRNA-Smad7 mediates cross-talk between Nodal/TGF-β and BMP signaling to regulate cell fate determination of pluripotent and multipotent cells
LC-MS/MS combined with the ChIRP for the mESCs of WT and lncRNA-Smad7 KO
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD036394 | Pride
Mouse lc-ms/ms mescs chirp 
ProteomicsCross-tissue deep profiling of redox proteome in obese mice
Cellular redox state, the balance between oxidation and reduction, is precisely regulated through cysteine thiol modification. In this study, we developed a novel method, in conjunction with directed data-independent acquisition (dDIA) for identifying and quantifying a substantial number of sulfhydr...
ORGANISM(S): Mus Musculus 
PXD066139 |
Metabolomics215 Tea plant metabolomics data
215 Tea plant metabolomics data
2025-12-23 | OEX00032869 | NODE
ProteomicsLiquid chromatography mass spectrometry-based nontargeted metabolomics predicts prognosis of hepatocellular carcinoma after curative resection
Assessment and prediction of prognostic risk in patients with hepatocellular carcinoma (HCC) would greatly benefit the optimal treatment selection. Here, we aimed to identify the critical metabolites associated with the outcomes and develop a risk score to assess the prognosis of HCC patients after ...
ORGANISM(S): Homo Sapiens 
PXD019864 |
Sort   by:  
 Page size