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MetabolomicsThe Manchurian Walnut Genome: Insights into Juglone and Lipid Biosynthesis

BACKGROUND: Manchurian walnut (Juglans mandshurica Maxim.) is a tree with multiple industrial uses and medicinal properties in the Juglandaceae family (walnuts and hickories). J. mandshurica produces juglone, which is a toxic allelopathic agent and has potential utilization value...

2022-05-18 | MTBLS3657 | MetaboLights
ProteomicsComparative proteome analyses of Ophiocordyceps sinensis at different stages
In this study, using an iTRAQ quantitative approach coupled with LC-MS/MS and bioinformatics, the proteomes were analyzed for the major three stages covering the fruiting body developmental process, including sclerotium (ST), primordium (PR) and mature fruiting body (MF), with a focus on fruiting bo...
ORGANISM(S): Ophiocordyceps Sinensis 
2020-09-01 | PXD021260 |
ProteomicsInvestigating the Therapeutic Impact of Traditional Chinese Medicine on Asthma through Proteomic Sequencing of Mouse Lung Tissue
Construct asthma mouse models using OVA and CFA, intervene with Warming Yang and Nourishing Kidney Approach and Xiao Qinglong Decoction respectively, and perform proteomic sequencing on the lung tissues of mice from control group-1, model group-1 and warming yang and tonifying kidney therapy group, ...
ORGANISM(S): Mus Musculus 小家鼠 
2024-11-15 | PXD058120 |
ProteomicsPhosphoproteomics attributes aberrant signaling events to a druggable kinome in hepatocellular carcinom
To connect aberrant phospho-signaling events to therapeutic vulnerabilities in hepatocellular carcinoma (HCC), we performed a mass-spectrometry-based phosphoproteomic quantification of human HCC tumors, adjacent tissues and cell lines. We developed an integrated pipeline as the inference of druggabl...
ORGANISM(S): Homo Sapiens 
2023-01-02 | PXD023840 |
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