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The Mediator complex functions as a control center orchestrating diverse signalings, gene activities, and biological processes. However, how Mediator subunits determine distinct cell fates remains to be fully elucidated. Here, we show that Mediator MED23 controls the cell fate preference that direct...
ORGANISM(S): Mus musculus 
O-GlcNAc proteins in LNM and non-LNM breast tumors of IDCs were identified by using the strategy of chemo-enzymatic labeling in combination with click chemistry and LC-MS/MS.
ORGANISM(S): Homo sapiens (Human) 
2015-09-22 | PXD002208 | Pride
A total of 6,526 proteins were identified in this study, of which 5880 proteins contained quantitative information. 1.2 times as the threshold of differential expression change, and statistical test t-test p-value<0.05 as the threshold of significance, among the quantified proteins, the expression...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026559 | Pride
Recently the membrane vesicles (MVs) production has been observed in Gram-positive bacterium, Cutibacterium acnes (C. acnes). In order to explore the mechanism of antibiotic resistance and the virulent components within the C. acnes-derived MVs, we isolated MVs from the clinical C. acnes, which were...
ORGANISM(S): Cutibacterium acnes SK137 
2022-05-20 | PXD025460 | Pride
Activated hepatic stellate cell (HSC) is the main myofibroblast cell in the liver fibrosis(LF). An important characteristic of the recovery of LF is not only the apoptosis of activated HSCs but also reversal of myofibroblast-like phenotype to a quiescent-like phenotype. Understanding the changes of ...
ORGANISM(S): Homo sapiens (Human) 
2014-08-11 | PXD000773 | Pride
To identify the heterogeneity of aBLA and pBLA at protein level, TMT labeled-Quantitative Proteomics strategy was applied.
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD016515 | Pride
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