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ProteomicsProteomics analysis on SETD2 loss induced ccRCC formation
Patients with polycystic kidney disease (PKD) encounter a high risk of clear cell renal cell carcinoma (ccRCC), a malignant tumor with dysregulated lipid metabolism. SET domain–containing 2 (SETD2) has been identified as an important tumor suppressor gene in ccRCC. However, the role of SETD2 in tumo...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-31 | PXD038966 | Pride
Polycystic kidney disease (pkd) Set domain–containing 2 (setd2) Clear cell renal cell carcinoma (ccrcc) 
MetabolomicsA new perspective on semen quality of aged male: The characteristics of metabolomics and proteomics

BACKGROUND: Semen quality is negatively correlated with male age and is mainly quantified by a routine semen analysis, which is descriptive and inconclusive. Sperm proteins or semen metabolites are used as the intermediate or end-products, reflecting changes in semen quality, an...

2024-01-16 | MTBLS5289 | MetaboLights
ProteomicsSpiDe-Sr: blind super-resolution network for precise cell segmentation and clustering in spatial proteomics imaging
Spatial proteomics elucidates cellular biochemical changes with unprecedented topological level. Imaging mass cytometry (IMC) is a high-dimensional single-cell resolution platform for targeted spatial proteomics. However, the precision of subsequent clinical analysis is constrained by imaging noise ...
ORGANISM(S): Homo Sapiens 
2024-02-25 | PXD050123 |
Proteomicssperm proteome of aged and young males
we build the sperm proteome profile of aged and young males
ORGANISM(S): Homo Sapiens 
PXD035466 |
ProteomicsProtective Effects of Pt-N-C Nanozymes against Myocardial Ischemia-reperfusion Injury
Effective therapeutic strategies for myocardial ischemia/reperfusion (I/R) injury are still lacking. Targeting reactive oxygen species (ROS), the major cause of I/R injury, provides a practical approach to alleviate myocardial damage after reperfusion procedure. Herein, we synthesized an innovative ...
ORGANISM(S): Mus Musculus 
2024-01-16 | PXD048584 |
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