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GenomicsMutational evolution in a lobular breast tumour profiled at single nucleotide resolution
We have used next generation sequencing to sequence genomes (>43-fold coverage) and transcriptomes of an oestrogen-receptor-alpha-positive metastatic lobular breast cancer at depth. We found 32 somatic non-synonymous coding mutations present in the metastasis, and measured the frequency of these som...
EGAS00000000054 | EGA
GenomicsEGAD00000000047
Signal data for from 3 recurrent and 1 ovarian primary Granulosa Cell Tumour samples
EGAD00000000047 | EGA
GenomicsEGAD00000000048
Sequencing data from oestrogen-receptor-alpha-positive metastatic lobular breast cancer sample
EGAD00000000048 | EGA
GenomicsEGAD00000000049
RNA-SEQ data from oestrogen-receptor-alpha-positive metastatic lobular breast cancer sample
EGAD00000000049 | EGA
GenomicsEGAD00000000046
RNA-SEQ data from 3 recurrent and 1 ovarian primary Granulosa Cell Tumour samples
EGAD00000000046 | EGA
GenomicsMutation of FOXL2 in granulosa cell tumors of the ovary
We generated paired-end RNA-Seq data using the Illumina Genome Analyzer II platform for four adult granulosa cell tumours (GCTs) of the ovary (1 primary, 3 recurrent). We screened this data for the presence of GCT specific sequence variants and detected a non-synonymous mutation in the FOXL2 gene th...
EGAS00000000040 | EGA
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