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UnknownEndogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency.
Not available
S-EPMC7021672 | biostudies-literature
UnknownThe dual pathway inhibitor rigosertib is effective in direct patient tumor xenografts of head and neck squamous cell carcinomas.
Not available
S-EPMC3796006 | biostudies-literature
TranscriptomicsAnalysis of Spt16 depletion
Transcription rate analysis in Yeast by means of GRO, mRNA amount and ChIP-on-chip during the depletion of Spt16p. Keywords: Genomic run-on GRO ChIP-chip Transcription rate analysis by means of GRO and mRNA amount (RA) of three independent replicates during the depletion of Spt16p (Control and 5 &...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-14082 | biostudies-arrayexpress
TranscriptomicsGene category-specific regulation of transcription elongation across the yeast genome
Analysis of genome-wide differences of transcription using Genomic run-on (GRO), RNApol II ChIP-on-Chip, cDNA analysis and ChIP-on-Chip. This SuperSeries is composed of the following subset Series: GSE14060 RNA pol II ChIP on chip (RPCC) GSE14077 RPCC analysis of rap1-sil, tpk1 & tpk2 GSE14080 ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-14084 | biostudies-arrayexpress
UnknownCRB2 completes a fully expressed Crumbs complex in the Retinal Pigment Epithelium.
Not available
S-EPMC4585915 | biostudies-literature
ProteomicsSARS-CoV-2 variants evolve convergent strategies to remodel the host response: Affinity Purification Mass Spectrometry (APMS)
We sought to compare differences in the SARS-CoV-2 virus-human protein interaction networks between mutated (from the SARS-CoV-2 variants of concern) and wild-type viral proteins. Here, we ectopically expressed 2x-strep-tagged constructs encoding mutant or wild-type SARS-CoV-2 viral proteins in HEK2...
ORGANISM(S): Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2024-02-16 | PXD036798 | Pride
Omics Apms Lung Sars-cov-2 Host response Host Infection Covid-19 Protein-protein interactions 
ProteomicsSARS-CoV-2 variants evolve convergent strategies to remodel the host response: Infection proteomics
We sought to compare differences in the human cellular response to distinct SARS-CoV-2 variants of concern. Here, we infected Calu-3 lung epithelial cells with each of the SARS-CoV-2 variants of concern (Alpha, Beta, Gamma, Delta, and Omicron) compared to two early-lineage controls (VIC and IC19). W...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2024-02-16 | PXD036968 | Pride
Lung Omics Sars-cov-2 Host response Host Infection Covid-19 
UnknownIntegrated variant allele frequency analysis pipeline and R package: easyVAF.
Not available
S-EPMC10843735 | biostudies-literature
UnknownInsight and benefits from vaccine clinical trials with adaptive designs: a scoping review.
Not available
S-EPMC12518217 | biostudies-literature
UnknownA Degenerate Metal-Templated Catalytic System with Redundant Functional Groups for the Asymmetric Aldol Reaction.
Not available
S-EPMC9171831 | biostudies-literature
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