To identify human DTX2 proximal proteome, the BioID-DTX2 fusion protein was expressed in DTX2 KO HeLa cells. The biotinylated proteins were pulled down and subjected to mass spectrometry analysis.
Abstract Objective: Epilepsy is a prevalent neurological disorder marked by seizures due to abnormal brain neuron discharge. Its pathological mechanism remains incompletely understood. This study utilizes transcriptomic and proteomic analyses on epileptic lesions from patients and brain tissue from ...
