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UnknownCACNA1C rs1006737 SNP increases the risk of essential hypertension in both Chinese Han and ethnic Russian people of Northeast Asia.

Abstract

Voltage-gated Ca2+ channels play a key role in the regulation of arterial tone and blood pressure. The aim of this study was to determine whether the association of calcium voltage-gated channel subunit alpha1 C (CACNA1C) rs1006737 with essential hypertension (EH) exists in both Chi...
S-EPMC7909128 | biostudies-literature
TranscriptomicsRadiation-induced changes in gene expression in the silkworm revealed by serial analysis of gene expression
These results provide valuable information for understanding the mechanisms of radiation-induced changes in gene expression.
ORGANISM(S): Bombyx mori 
2005-06-20 | E-GEOD-2689 | biostudies-arrayexpress
ProteomicsSWATH-MS quantitative analysis of proteins in the rice inferior and superior spikelets during grain filling
Modern rice cultivars have large panicle, however, yield potential of these cultivars is often not fully achieved due to the poor grain-filling of their late-flowering inferior spikelets (IS). Our earlier work suggests broad transcriptional reprogramming during grain filling and shows a difference i...
ORGANISM(S): Oryza sativa (Rice) 
2017-07-03 | PXD005401 | Pride
Proteomics Swath-ms analysis Grain filling Rice. Post-transcriptional regulation 
UnknownAssessment of HCMV-encoded microRNAs in plasma as potential biomarkers in pregnant women with adverse pregnancy outcomes.

Background

Human cytomegalovirus (HCMV) is the most frequent cause of congenital infections and can lead to adverse pregnancy outcomes (APOs). HCMV encodes multiple microRNAs (miRNAs) that have been reported to be partially related to host immune responses, cell cycle regulation, viral repli...
S-EPMC8106018 | biostudies-literature
ProteomicsCoordinate Enhancer Reprogramming by GATA3 and AP1 Promotes Phenotypic Plasticity to Achieve Breast Cancer Endocrine Resistance
Phenotypic plasticity has emerged as an important mechanism of therapy resistance in cancers, yet the underlying molecular mechanisms remain unclear. Using an established breast cancer cellular model for endocrine resistance, we show that hormone resistance is associated with enhanced phenotypic pla...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-24 | MSV000083857 | MassIVE
Genomics32c6825c-80c0-4d0f-9284-cc7c1a39e68a - samples
Whole transcriptome sequencing (RNA-seq) was performed on 39 PC specimens. Among them, 21 specimens also had WES data.
EGAD00001004365 | EGA
Genomicsc9d38693-41de-4186-90c3-5e52d1913254 - samples
Whole-exome sequencing (WES) was performed on a total of 34 PC specimens, with 15 cases having matched gDNAs extracted from blood.
EGAD00001004364 | EGA
GenomicsProfiling of Peritoneal Metastases from Gastric Adenocarcinoma Identified Molecular Subtypes
Peritoneal carcinomatosis (PC) occurs frequently in gastric adenocarcinoma (GAC) patients and confers poor prognosis. Multiplex profiling of primary GACs has been insightful but the underpinnings of PC’s development/progression remain largely unknown. Here we characterized exome/transcriptome/immune...
EGAS00001003180 | EGA
GenomicsData Access Commitee for gastric cancer ascites
Data Access Committee EGAC00001001026
EGAC00001001026 | EGA
ProteomicsAntipsychotic cardiotoxicity and its mechanisms
Antipsychotic (AP) drugs are common agents for treating mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. Overall AP prescription increased 3.8-fold, while second-generation AP (SGA) prescriptions increased 18.1-fold during a 16-year follow-up. The increased us...
ORGANISM(S): Mus Musculus 
2021-12-22 | PXD030588 |
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