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UnknownEffects of low level laser on periodontal tissue remodeling in hPDLCs under tensile stress.
Not available
S-EPMC10567958 | biostudies-literature
GenomicsIntegrating 5 Hydroxymethylcytosine into the Epigenetic Landscape of Human Embryonic Stem Cells
Covalent modification of DNA distinguishes cellular identities and is crucial for regulating the pluripotency and differentiation of embryonic stem (ES) cells. The recent demonstration that 5-methylcytosine (5-mC) may be further modified to 5-hydroxymethylcytosine (5-hmC) in ES cells has revealed a ...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-30173 | biostudies-arrayexpress
MetabolomicsChromosome‐level genome of Camellia lanceoleosa provides a valuable resource for understanding genome evolution and self‐incompatibility

The section Oleifera (Theaceae) has attracted attention for the high levels of unsaturated fatty acids found in its seeds. Here, we report the chromosome-scale genome of the sect. Oleifera using diploid wild Camellia lanceoleosa with a final size of 3.00 Gb and an N50 s...

2022-07-14 | MTBLS3769 | MetaboLights
ProteomicsInteraction proteins of cGAS and PSMA4 with lactate treatment
Sample 1: Control Sample 2: Interaction proteins of Flag-cGAS Sample 3: Interaction proteins of Flag-cGAS with lactate treatment Sample 4: Interaction proteins of Flag-PSMA4 Sample 5: Interaction proteins of Flag-PSMA4 with lactate treatment
ORGANISM(S): Homo sapiens (Human) 
2025-03-21 | PXD053886 | Pride
Lactate Psma4 Cgas 
Genomics5-hydroxymethylcytosine-mediated epigenetic dynamics during neurodevelopment and aging [5hmC Capture and Seq]
DNA methylation dynamics influence brain function and are altered in neurological disorders. 5-hydroxymethylcytosine (5-hmC), a DNA base derived from 5-methylcytosine (5mC) accounts for ~40% of modified cytosine in brain, and has been implicated in DNA methylation-related plasticity. Here we map 5-h...
ORGANISM(S): Mus musculus 
2011-10-30 | E-GEOD-32050 | biostudies-arrayexpress
UnknownIn vivo adenine base editing corrects newborn murine model of Hurler syndrome.
Not available
S-EPMC9947215 | biostudies-literature
GenomicsSelective chemical labeling reveals intragenic enrichment of 5-hydroxymethylcytosine in mouse cerebellum
5-Methylcytosine (5-mC) is an important DNA modification found in eukaryotes that impacts gene regulation and disease pathogenesis. Recently, 5-hydroxymethylcytosine (5-hmC), another form of DNA modification, has been identified in substantial amounts in certain mammalian cell types; however, its ro...
ORGANISM(S): Mus musculus 
2010-12-12 | E-GEOD-25398 | biostudies-arrayexpress
UnknownLiver-directed gene therapy corrects neurologic disease in a murine model of mucopolysaccharidosis type I-Hurler.
Not available
S-EPMC9065053 | biostudies-literature
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownDelivery of nVEGFi using AAV8 for the treatment of neovascular age-related macular degeneration.
Not available
S-EPMC8800040 | biostudies-literature
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