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MetabolomicsGlobal metabolomics of fireflies (Coleoptera: Lampyridae) explore metabolic adaptation to fresh water in insects

Aquatic insects are well-adapted to freshwater environments, but metabolic mechanisms of such adaptations, particularly to primary environmental factors (e.g., hypoxia, water pressure, dark light and abundant microbes), are poorly known. Most firefly species (Coleoptera: Lampyridae) are terrestri...

2022-10-03 | MTBLS4987 | MetaboLights
UnknownExpression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts.
Not available
S-EPMC3770002 | biostudies-literature
TranscriptomicsTCF7 is a key regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line
A critical problem in biology is understanding how cells choose between self-renewal and differentiation. To generate a comprehensive view of the mechanisms controlling early hematopoietic precursor self-renewal and differentiation, we used systems-based approaches and murine EML multipotential hema...
ORGANISM(S): Mus musculus 
2012-03-29 | E-GEOD-30068 | biostudies-arrayexpress
GenomicsThe alteration of 5-hydroxymethylcytosine modification contributes to ischemic brain injury [5hmC-seq]
Epigenetic modifications, such as cytosine methylation and histone modification, have been shown involved in the pathology of ischemic brain injury. Recent works have implicated 5-hydroxymethylcytosine (5hmC), a DNA base derived from 5-methylcytosine (5mC) through the oxidation by Ten-Eleven Translo...
ORGANISM(S): Mus musculus 
2015-09-08 | E-GEOD-67188 | biostudies-arrayexpress
MetabolomicsSemen Cuscutae flavonoids activated the cAMP-PKA-CREB-BDNF pathway and exerted an antidepressant effect in mice

Background: Semen Cuscutae flavonoids (SCFs) constitute a class of metabolites of Semen Cuscutae, a botanical drug that was recently found to have an anti-depression effect. This study aimed to evaluate the anti-depression effects of SCFs in chronic unpredi...

2025-05-12 | MTBLS11688 | MetaboLights
UnknownReplicative bypass studies of l-deoxyribonucleosides in Vitro and in E. coli cell.
Not available
S-EPMC9729220 | biostudies-literature
TranscriptomicsGene expression profiling of mouse prostate over-expressing the Notch1 intracellular domain.
Molecular signaling that regulates differentiation, survival and proliferation of the prostate luminal epithelial cells has not been thoroughly understood. Herein, we show that increased canonical Notch1 activity suppresses terminal differentiation of prostate luminal epithelial cells but is insuffi...
ORGANISM(S): Mus musculus 
2014-08-07 | E-GEOD-53036 | biostudies-arrayexpress
UnknownProteomic analysis of liver mitochondria from rats with nonalcoholic steatohepatitis.
Not available
S-EPMC4000516 | biostudies-literature
UnknownSex Differences of Cardiolipin in Tissue Distribution Based on Targeted Lipidomic Analysis by UHPLC-QTOF-MS/MS.
Not available
S-EPMC9612025 | biostudies-literature
UnknownEffect of education on endometriosis and mediating effects: a mendelian randomization study.
Not available
S-EPMC12414883 | biostudies-literature
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