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TranscriptomicsHOXB7 is an ERα cofactor in the activation of HER2 and multiple ER target genes leading to endocrine resistance
Why breast cancers become resistant to tamoxifen despite continued expression of the estrogen receptor alpha (ERα) and what factors are responsible for high HER2 expression in these tumors remains an enigma. HOXB7 ChIP analysis followed by validation showed that HOXB7 physically interacts with ERα...
ORGANISM(S): Homo sapiens 
2014-11-25 | E-GEOD-63607 | biostudies-arrayexpress
TranscriptomicsCleavage of NIK by the API2-MALT1 Fusion Oncoprotein Leads to Noncanonical NF-{kappa}B Activation
Proper regulation of nuclear factor κB (NF-κB) transcriptional activity is required for normal lymphocyte function, and deregulated NF-κB signaling can facilitate lymphomagenesis. We demonstrate that the API2-MALT1 fusion oncoprotein created by the recurrent t(11;18)(q21;q21) in mucosa-associated ly...
ORGANISM(S): Homo sapiens 
2011-01-30 | E-GEOD-25527 | biostudies-arrayexpress
UnknownACMSD methylation in peripheral blood is associated with dynamic functional connectivity pattern in adolescent MDD patients.
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S-EPMC12452479 | biostudies-literature
UnknownA BSL-2 compliant mouse model of SARS-CoV-2 infection for efficient and convenient antiviral evaluation.
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S-EPMC11265351 | biostudies-literature
UnknownProtein acetylation in mitochondria plays critical functions in the pathogenesis of fatty liver disease.
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S-EPMC7318365 | biostudies-literature
UnknownIdentification of PSMB5 as a genetic modifier of fragile X-associated tremor/ataxia syndrome.
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S-EPMC9295734 | biostudies-literature
UnknownDepletion of EREG enhances the osteo/dentinogenic differentiation ability of dental pulp stem cells via the p38 MAPK and Erk pathways in an inflammatory microenvironment.
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S-EPMC8215766 | biostudies-literature
UnknownProfiling ATM regulated genes in Drosophila at physiological condition and after ionizing radiation.
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S-EPMC9587650 | biostudies-literature
UnknownEffects of brewers' spent grain protein hydrolysates on gas production, ruminal fermentation characteristics, microbial protein synthesis and microbial community in an artificial rumen fed a high grain diet.
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S-EPMC7780661 | biostudies-literature
UnknownFacile fabrication of hierarchical ultrathin Rh-based nanosheets for efficient hydrogen evolution.
Not available
S-EPMC10167732 | biostudies-literature
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