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GenomicsSubsets of visceral adipose tissue nuclei with discrete levels of 5-hydroxymethylcytosine
We explored the hypothesis that adipose tissue contains epigenetically distinct subpopulations of adipocytes that are differentially potentiated to record cellular memories of their environment. Adipocytes are large, fragile, and technically difficult to efficiently isolate and fractionate. We devel...
ORGANISM(S): Sus scrofa 
2016-07-20 | E-GEOD-73684 | biostudies-arrayexpress
GenomicsDNA Cytosine Hydroxymethylation Levels Are Distinct Among Peripheral Blood Leukocytes
Peripheral blood leukocytes are the most commonly used surrogates to study epigenome-induced risk and epigenomic response to disease related stress. We considered the hypothesis that the TET enzyme catalyzed hydroxymethylation of 5mC to 5hmC might vary among peripheral blood leukocytes and reflect t...
ORGANISM(S): Homo sapiens 
2016-07-05 | E-GEOD-70519 | biostudies-arrayexpress
UnknownA Silver Yarn-Incorporated Song Brocade Fabric with Enhanced Electromagnetic Shielding.
Not available
S-EPMC8307523 | biostudies-literature
UnknownProtective effect of compatible herbs in Jin-Gu-Lian formula against Alangium chinense-induced neurotoxicity via oxidative stress, neurotransmitter metabolisms, and pharmacokinetics.
Not available
S-EPMC9977795 | biostudies-literature
ProteomicsStructural O-Glycoform Heterogeneity of the SARS-CoV-2 Spike Protein Receptor-Binding Domain Revealed by Top-Down Mass Spectrometry
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes an extensively glycosylated surface spike (S) protein to mediate host cell entry and the S protein glycosylation plays key roles in altering viral binding/function and infectivity. However, the molecular structures and glycan hete...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-07-27 | MSV000087891 | MassIVE
TranscriptomicsCombined loss of Tet1 and Tet2 promotes B-cell, but not myeloid malignancies in mice
TET1/2/3 are methylcytosine dioxygenases regulating cytosine hydroxymethylation in the genome. Tet1 and Tet2 are abundantly expressed in HSC/HPCs and implicated in the pathogenesis of hematological malignancies. Tet2-deletion in mice causes myeloid malignancies, while Tet1-null mice develop B-cell l...
ORGANISM(S): Mus musculus 
2015-11-12 | E-GEOD-73611 | biostudies-arrayexpress
UnknownPositive Regulation of the Antiviral Activity of Interferon-Induced Transmembrane Protein 3 by S-Palmitoylation.
Not available
S-EPMC9236556 | biostudies-literature
UnknownSex Differences of Cardiolipin in Tissue Distribution Based on Targeted Lipidomic Analysis by UHPLC-QTOF-MS/MS.
Not available
S-EPMC9612025 | biostudies-literature
MetabolomicsChromosome‐level genome of Camellia lanceoleosa provides a valuable resource for understanding genome evolution and self‐incompatibility

The section Oleifera (Theaceae) has attracted attention for the high levels of unsaturated fatty acids found in its seeds. Here, we report the chromosome-scale genome of the sect. Oleifera using diploid wild Camellia lanceoleosa with a final size of 3.00 Gb and an N50 s...

2022-07-14 | MTBLS3769 | MetaboLights
UnknownInjury of Macrophages Induced by Clostridium perfringens Type C Exotoxins.
Not available
S-EPMC11011396 | biostudies-literature
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