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ProteomicsMLKL confers ferroptosis resistance in colorectal cancer cells via impaired ESCRT-III-mediated membrane repair
Mixed lineage kinase domain-like protein (MLKL) is well established as the executioner of necroptosis, but emerging evidence suggests broader functions beyond necroptosis. Our bioinformatic analyses revealed that MLKL expression positively correlates with glutathione metabolism–related genes in colo...
ORGANISM(S): Homo sapiens (Human) 
2026-10-05 | PXD078766 | Pride
Mlkl Ferroptosis Colorectal cancer 
TranscriptomicsOvercoming chemoresistance in B lymphoma cells: elucidating the role of NF-kB in caspase-independent apoptosis by transcriptomic assessment.
Although therapy responsiveness to therapy in Burkitt lymphoma (BL) is high, relapsed disease and and chemoresistance remain a clinical challenge, and complete mechanisms underlying BL chemoresistance and how it can be circumvented is yet to be fully elucidated. In this study we present data showing...
ORGANISM(S): Homo sapiens 
2014-01-19 | E-GEOD-31258 | biostudies-arrayexpress
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