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TranscriptomicsTranscription profiling of mouse CD4+CD8+ thymocytes following engagement of TCR with anti-Valpha or Vbeta antibodies
Comparison of gene expression changes in CD4+CD8+ thymocytes following engagement of TCR with anti-Valpha or Vbeta antibodies
ORGANISM(S): Mus musculus 
2007-09-28 | E-GEOD-1448 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing data from murine hearts after infarction with endothelial tracing
Data set contains samples from isolated cells of murine hearts after myocardial infarction (LAD surgery). We used an endothelial tracing system to mark endothelial cells with EGFP prior to infarct. In brief, Cdh5-ERT2+/-;mT/mG mice, which were used at an age of 10-12 weeks. Cre expression was induc...
ORGANISM(S): Mus musculus 
2020-12-15 | E-MTAB-9816 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNA sequencing data from murine hearts after infarction with Collagen-2 tracing
Data set contains samples from isolated cells of murine hearts after myocardial infarction (LAD surgery). We used Col1a2 tracing system to mark Collagen expressing cells within d3 to d7 post infarct. In brief, adult Col1a2-ERT2+/-;mT/mG mice, at an age of 12 weeks (n=4) as well as aged animals with ...
ORGANISM(S): Mus musculus 
2020-12-15 | E-MTAB-9817 | biostudies-arrayexpress
GenomicsChIP-Seq of BCL11A and SOX2 in lung squamous cell carcinoma (LUSC) LK-2 cell line with or without BCL11A knockdown
BCL11A is upregulated in lung squamous cell carcinoma (LUSC) but not in lung adenocarcinoma (LUAD). BCL11A interacts with SOX2 at protein level. ChIP-Seq experiment was performed for BCL11A and SOX2 in LUSC LK-2 control or BCL11A-KD cell line in order to identify their role in LUSC pathology.
ORGANISM(S): Homo sapiens 
2018-07-05 | E-MTAB-6958 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic fibroblasts (MEF) during adipocyte differentiation timeseries
Gene expression timeseries analysis of mouse embryonic fibroblasts (MEF) during differentiation to mature adipocytes with a 27.648 element murine cDNA microarray. Three independent time series experiments of MEF adipocyte differentiation were performed in reference design. RNA from 7 time points (0d...
ORGANISM(S): Mus musculus 
2010-01-20 | E-MARS-13 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic fibroblasts Rb-/- MEF (ME3) and Rb+/+ MEF (MEFA) during adipocyte differentiation
Gene expression of Retinoblastoma deficient mouse embryonic fibroblasts (Rb-/- MEF, ME3) and wildtype mouse embryonic fibroblasts (Rb+/+ MEF,MEFA) during adipocyte differentiation were studied by cDNA microarray analysis. 2-day postconfluent cells (day 0) were treated with a hormonal cocktail includ...
ORGANISM(S): Mus musculus 
2010-01-20 | E-MARS-12 | biostudies-arrayexpress
TranscriptomicsInfluence of RNA Labeling on Expression Profiling of MicroRNAs
Several technical parameters are now being optimized for microRNA expression profiling experiments, but the finite amount of total RNA available continues to bottleneck clinical investigations. We used microarrays to determine the influence of the labeling reagent on total RNA requirements and data ...
ORGANISM(S): synthetic construct 
2012-05-21 | E-GEOD-30045 | biostudies-arrayexpress
TranscriptomicsmCG-PML-RARA alters multipotent hematopoiesis.
Acute promyelocytic leukemia (APL) is associated with PML-RARA expression and late myeloid maturation arrest. The myeloid restriction of PML-RARA dependent leukemia has been recapitulated in multiple mouse models of APL, including PML-RARA expressed from the Ctsg locus (mCG-PR). However, we report h...
ORGANISM(S): Mus musculus 
2010-10-21 | E-GEOD-24728 | biostudies-arrayexpress
TranscriptomicsExpression and function of PML-RARA in the multipotent hematopoietic progenitor cells of Ctsg-PML-RARA mice
Because PML-RARA-positive acute promyelocytic leukemia (APL) is a morphologically differentiated leukemia, much speculation has been made about whether its leukemic cell of origin might be committed myeloid precursor (e.g., a promyelocyte) vs. a hematopoietic stem/progenitor cell (HSPC). We original...
ORGANISM(S): Mus musculus 
2012-08-13 | E-GEOD-40022 | biostudies-arrayexpress
UnknownCaveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling
Not available
S-JCBD-201307055 | bioimages
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