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MetabolomicsComparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth
Bacteria need nutrients from the host environment to survive, yet we know little about which biochemicals are present in the airways (the metabolome), which of these biochemicals are essential for bacterial growth and how they change with airway disease. The aims of this pilot study were to develop ...
2019-06-13 | MTBLS179 | MetaboLights
UnknownFormaldehyde regulates <i>S</i>-adenosylmethionine biosynthesis and one-carbon metabolism.
Not available
S-EPMC11500418 | biostudies-literature
GenomicsChIP-seq analysis of H3K9me3 levels across the genome for one copy of H3K9M mutant in pombe
We performed ChIP-seq analyses for WT, H3K9M mutant and clr4 mutant in Schizosaccharomyces pombe, and showed that H3K9me3 level was reduced to background levels across the entire genome, similar to clr4 mutant.
ORGANISM(S): Schizosaccharomyces pombe 
2016-10-03 | E-MTAB-4776 | biostudies-arrayexpress
ProteomicsS. coelicolor M1146 pCAPbtm1 and pCAPbtm5 Synapt analysis
pCAPbtm1 and pCAPbtm5 expressed in S. coelicolor M1146.
ORGANISM(S): Streptomyces Coelicolor M1146 
2018-04-06 | MSV000082245 | MassIVE
TranscriptomicsInhibitors that block initiation of wall teichoic acid biosynthesis sensitize methicillin-resistant Staphylococcus aureus to beta-lactams
Methicillin resistance in Staphylococcus aureus depends on the production of mecA, which encodes penicillin-binding protein 2A (PBP2A), an acquired peptidoglycan transpeptidase with reduced susceptibility to beta-lactam antibiotics. Here, we show that preventing the expression of wall teichoic acids...
ORGANISM(S): Staphylococcus aureus 
2010-10-19 | E-GEOD-24439 | biostudies-arrayexpress
UnknownWatasemycin biosynthesis in <i>Streptomyces venezuelae</i>: thiazoline C-methylation by a type B radical-SAM methylase homologue.
Not available
S-EPMC5427693 | biostudies-literature
TranscriptomicsTea tree oil induced transcriptional alterations in Staphylococcus aureus
S. aureus and MRSA are susceptible to TTO and are therefore targeted in nascent TTO clinical trails. We now report the alterations in the transcriptome of a S. aureus exposed to a growth inhibitory concentration of TTO. These efforts have uncovered additional mechanisms by which this membrane active...
ORGANISM(S): Staphylococcus aureus 
2012-04-25 | E-GEOD-31554 | biostudies-arrayexpress
TranscriptomicsDifferentiating Arabidopsis shoots from leaves by combined YABBY activities
In seed plants, leaves are born on radial shoots but unlike shoots they are determinate dorsiventral organs made of flat lamina. YABBY genes are found only in seed plants and in all cases studied, are expressed primarily in lateral organs and in a polar manner. Despite their simple expression, Arabi...
ORGANISM(S): Arabidopsis thaliana 
2010-08-01 | E-GEOD-21705 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptional profiling of Saccharomyces cerevisiae treated with thymol
We employed CapitalBio Corporation to investigate the global transcriptional profiling of Saccharomyces cerevisiae treated with thymol. Keywords: gene expression array-based, count S. cerevisiae strain L1190 was incubated in a rotary shaker. Subsequently, thymol was added to the culture and DMSO to...
ORGANISM(S): Saccharomyces cerevisiae 
2008-08-05 | E-GEOD-12329 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptional profiling of Saccharomyces cerevisiae treated with dictamnine
We employed CapitalBio Corporation to investigate the global transcriptional profiling of Saccharomyces cerevisiae treated with dictamnine. S. cerevisiae strain L1190 was incubated in a rotary shaker. Subsequently, dictamnine was added to the culture and DMSO to the control. Then, the yeast cells ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-25 | E-GEOD-9817 | biostudies-arrayexpress
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