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ProteomicsARIH2 is a novel Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection
Discovery of novel host-virus interactions leads to a better understanding of mechanisms underlying infection and points to potential therapeutic targets at the interface between virus and host proteins. Recently, global, virus-host interaction networks have been mapped using affinity purification-m...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-01-29 | MSV000084855 | MassIVE
TranscriptomicsFoxA1 regulates sweat secretion through Best2 and Nkcc1 ion transporters
Body temperature is maintained in a narrow range in mammals, primarily controlled by sweating. In humans, the dynamic thermoregulatory organ, comprised of 2-4 million sweat glands distributed over the body, can secrete up to 4 liters of sweat per day1, thereby making it possible to withstand high te...
ORGANISM(S): Mus musculus 
2012-01-11 | E-GEOD-32347 | biostudies-arrayexpress
UnknownCNS neuroplasticity and salt-sensitive hypertension induced by prior treatment with subpressor doses of ANG II or aldosterone.
Not available
S-EPMC4159736 | biostudies-literature
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-CUL5
SRM assays were generated for selected interactors of CUL5. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084963 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-ELOB
SRM assays were generated for selected interactors of ELOB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084962 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM-CBFB
SRM assays were generated for selected interactors of CBFB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated from the shotgun M...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084964 | MassIVE
ProteomicsARIH2 is a Vif-dependent regulator of CUL5-mediated APOBEC3G degradation in HIV infection: SRM_CBFB_CUL2_CUL5_interactors
SRM assays were generated for selected interactors of CUL5, CBFB and ELOB. SRM assay generation was performed using Skyline. For all targeted proteins, proteotypic peptides and optimal transitions for identification and quantification were selected based on the Skyline spectral library generated fro...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Human Immunodeficiency Virus 1 (ncbitaxon:11676) 
2020-02-17 | MSV000084965 | MassIVE
TranscriptomicsExpression of MERTK based on Multiple Sclerosis (MS) risk haplotype
Whole transcriptome RNA-seq analysis to measure group-wise RNA expression level of the MERTK gene in 3 healthy controls (known to be homozygous non-risk haplotype at MERTK gene locus) and to compare this to the group-wise RNA expression level of the MERTK gene in 5 Multiple Sclerosis-affected (MS-af...
ORGANISM(S): Homo sapiens 
2016-02-06 | E-GEOD-77598 | biostudies-arrayexpress
UnknownGrand Challenges at the Interface of Engineering and Medicine.
Not available
S-EPMC10896418 | biostudies-literature
MetabolomicsMetabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
Global ageing poses a substantial economic burden on health and social care costs. Enabling a greater proportion of older people to stay healthy for longer is key to the future sustainability of health, social and economic policy. Frailty and associated decrease in resilience plays a central role in...
2019-09-06 | MTBLS598 | MetaboLights
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