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MetabolomicsSAR11 Cells Rely on Enzyme Multifunctionality to Transport and Metabolize a Range of Polyamine Compounds
In the ocean surface layer and cell culture, the polyamine transport protein PotD of SAR11 bacteria is often one of the most abundant proteins detected. Polyamines are organic cations at seawater pH produced by all living organisms and are thought to be an important component of dissolved organic ma...
2021-09-09 | MTBLS3146 | MetaboLights
TranscriptomicsTargeted disruption of BMAL1 in the peripheral reproductive axis results in infertility in female mice
The product of the Bmal1 locus is an essential component of the circadian clock that plays important roles in various aspects of reproductive biology,and when disrupted results in infertility. In an effort to establish the identity of the tissue specific clock that is responsible for this infertilit...
ORGANISM(S): Mus musculus 
2014-10-01 | E-GEOD-48758 | biostudies-arrayexpress
TranscriptomicsThe carbonic anhydrase inhibitor ethoxzolamide inhibits the Mycobacterium tuberculosis PhoPR regulon and Esx-1 secretion and attenuates virulence
The purpose of this study was to examine how ethoxzolamide modulates gene M. tuberculosis gene expression at acidic pH. We observed that ethoxzolamide downregulates genes of the PhoPR regulon. Mtb strain CDC1551 was grown at 37C in T-25 vented, standing tissue culture flasks in 8 ml of buffered 7H9 ...
ORGANISM(S): Mycobacterium tuberculosis 
2015-05-20 | E-GEOD-63917 | biostudies-arrayexpress
TranscriptomicsSingle Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex
The human cerebral cortex depends for its normal development and size on a precisely controlled balance between self-renewal and differentiation of diverse neural progenitor cells. Specialized progenitors that are common in humans, but virtually absent in rodents, called â??outer radial gliaâ?? (ORG...
ORGANISM(S): Homo sapiens 
2015-02-24 | E-GEOD-66217 | biostudies-arrayexpress
ProteomicsSimultaneous Optimization of Multi-lignocellulosic-sugar Catabolism via Systematic Laboratory Evolution in Dynamic Conditions
The development of microbial bioproduction is challenged by the complexity and variability of industrial feedstocks. This study aimed to systematically and simultaneously optimize catabolism of multiple sugars present in common renewable lignocellulose by adaptive laboratory evolution (ALE) using dy...
ORGANISM(S): Pseudomonas putida KT2440 
2026-06-29 | PXD055215 | Pride
Pseudomonas putida Adaptive laboratory evolution (ale) Proteomics Lignocellulose 
TranscriptomicsTranscription profiling of mouse macrophage responses to all-trans retinoic acid between wild type and NCoR-/- mice
Comparison of mouse macrophage responses to all-trans retinoic acid between wild-type and NCoR-/- mice.
ORGANISM(S): Mus musculus 
2006-11-06 | E-MEXP-37 | biostudies-arrayexpress
UnknownLeukocyte activity in patients with ST-segment elevation acute myocardial infarction treated with anakinra.
Not available
S-EPMC4277550 | biostudies-literature
TranscriptomicsTranscription profiling of mouse macrophage responses to lipopolysaccharide (LPS) and 12-o-tetradecanoylphorbol-13-acetate (TPA) in wild type and NcoR-/- mice
Comparison of mouse macrophage responses to lipopolysaccharide (LPS) and 12-o-tetradecanoylphorbol-13-acetate (TPA) between wild-type and NcoR-/- mice.
ORGANISM(S): Mus musculus 
2006-11-06 | E-MEXP-38 | biostudies-arrayexpress
TranscriptomicsTranscriptome signature in early biopsies of stably functioning kidney allografts identify patients at risk for chronic injury
Chronic injury in kidney transplants remains a major cause of graft loss. The aim of this study was to identify a predictive gene set capable of classifying renal grafts at risk for progressive injury due to fibrosis.The Genomics of Chronic Allograft Rejection (GoCAR) study is a prospective, multice...
ORGANISM(S): Homo sapiens 
2016-07-20 | E-GEOD-57387 | biostudies-arrayexpress
UnknownFactors Associated With Alcohol Use After Metabolic and Bariatric Surgery: Protocol for an Ecological Momentary Assessment.
Not available
S-EPMC12853087 | biostudies-literature
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