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ProteomicsPyruvate-supported flux through medium chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles
Even-chain acylcarnitine (AC) metabolites, most of which are generated as byproducts of incomplete fatty acid oxidation (FAO), are viewed as biomarkers of mitochondrial lipid stress attributable to one or more metabolic bottlenecks in the beta-oxidation pathway. The origins and functional implicatio...
ORGANISM(S): Mus Musculus (mouse) 
2023-04-14 | PXD040326 | JPOST Repository
ProteomicsKetone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding
Time-restricted feeding (TRF) has gained attention as a dietary regimen that promotes metabolic health. This study sought to determine if ketone flux in skeletal and cardiac muscles plays an essential role in conferring the health benefits of an intermittent TRF (iTRF) schedule. Notably, we found th...
ORGANISM(S): Mus Musculus (mouse) 
2024-02-09 | PXD047114 | JPOST Repository
ProteomicsMetformin Impairs Intestinal Fructose Metabolism
Objective: To investigate the effects of metformin on intestinal carbohydrate metabolism in vivo. Method: Male mice preconditioned with a high-fat, high-sucrose diet were treated orally with metformin or a control solution for two weeks. Fructose metabolism, glucose production from fructose, and p...
ORGANISM(S): Mus Musculus (mouse) 
2024-04-27 | PXD041833 | JPOST Repository
Genomicsicgc-liri-jp_release16 - samples
RIKEN collection WGS reads for 100 HCC and matched blood samples from 50 donors submitted to ICGC for release 16
EGAD00001000842 | EGA
Genomicsriken_wgs_mc_im_hcc - samples
RIKEN collection of WGS read of 59 multi-centric liver cancers or intra-haptatic metastasis and matched blood samples from 19 donors.
EGAD00001001643 | EGA
Genomicsena-DATASET-Genentech-13-10-2014-16:40:50:136-199 - samples
Whole genome data (Complete genomics platform) for the study EGAS00001000824
EGAD00001001034 | EGA
Genomicsrnaseq-22hcc - samples
RIKEN collection WGS and RNA-seq reads for 66 HBV-associated HCC and matched blood or liver samples from 22 donors.
EGAD00001001035 | EGA
Genomicsicgc-liri-jp_release15 - samples
RIKEN collection WGS reads for 321 HCC and blood matched samples from 158 donors submitted to ICGC for release 15
EGAD00001000808 | EGA
Genomicsriken_moim_wgs_13 - samples
RIKEN collection of WGS reads for 13 multicentric liver cancers or intrahepatic metastasis and matched blood samples for 12 donors.
EGAD00001001996 | EGA
Genomicsriken_wgs_hcc270 - samples
RIKEN collection of WGS reads of 530 liver cancer and matched blood samples from 260 donors.
EGAD00001001642 | EGA
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