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MetabolomicsChanges in lipid profiles of epileptic mouse model

INTRODUCTION: Approximately 1% of the world's population is impacted by epilepsy, a chronic neurological disorder characterized by seizures. One-third of epileptic patients are resistant to AEDs, or have medically refractory epilepsy (MRE). One non-invasive treatment that exists...

2022-01-06 | MTBLS1432 | MetaboLights
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 7 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33935 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus)
This SuperSeries is composed of the following subset Series: GSE33888: Neurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 1 of 10) GSE33893: Neurotoxicogenomic investigations to assess mechan...
ORGANISM(S): Colinus virginianus 
2011-11-22 | E-GEOD-27653 | biostudies-arrayexpress
MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 4 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33928 | biostudies-arrayexpress
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 6 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33934 | biostudies-arrayexpress
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 5 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33932 | biostudies-arrayexpress
UnknownShocked quartz at the Younger Dryas onset (12.8 ka) supports cosmic airbursts/impacts contributing to North American megafaunal extinctions and collapse of the Clovis technocomplex.
Not available
S-EPMC12422476 | biostudies-literature
UnknownHuman Leukocyte Antigen Class I Genes Associated With Stevens-Johnson Syndrome and Severe Ocular Complications Following Use of Cold Medicine in a Brazilian Population.
Not available
S-EPMC5470496 | biostudies-literature
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