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UnknownCombined BRAF (Dabrafenib) and MEK inhibition (Trametinib) in patients with BRAFV600-mutant melanoma experiencing progression with single-agent BRAF inhibitor.
Not available
S-EPMC4226803 | biostudies-literature
TranscriptomicsGenome-wide profiling of follicular lymphoma by array comparative genomic hybridization
The secondary genetic events associated with follicular lymphoma (FL) progression are not well defined. We applied genome-wide BAC array comparative genomic hybridization to 106 diagnostic biopsies of FL to characterize regional genomic imbalances. Using an analytical approach that defined region...
ORGANISM(S): Homo sapiens 
2010-05-25 | E-GEOD-12393 | biostudies-arrayexpress
TranscriptomicsGWAS region focused capture-HiC of primary melanocytes from five human donors
Capture-HiC was conducted to map chromatin interactions at all melanoma GWAS identified risk-associated regions across five individual primary human melanocyte cultures. Capture-HiC baits were designed by Arima Genomics (San Diego, CA, 2x tiling, least stringent masking, XTHSBoosting) to obtain an A...
ORGANISM(S): Homo sapiens 
2025-04-24 | E-MTAB-15079 | biostudies-arrayexpress
TranscriptomicsAssay for Transposase-Accessible Chromatin sequencing (ATAC-seq) of primary melanocytes from five human donors
ATAC-seq was conducted to map open chromatin regions in five individual primary human melanocyte cultures. The ATAC libraries were sequenced using paired-end sequencing on an Illumina NovaSeq platform. In total, we sequenced 15 ATAC libraries from these five independent primary melanocyte cultures (...
ORGANISM(S): Homo sapiens 
2025-04-24 | E-MTAB-15048 | biostudies-arrayexpress
TranscriptomicsSystematic evaluation of variability in simulated ChIP-chip experiments
The most widely-used method for detecting and measuring genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Many tiling array platforms, amplification methods, and analysis algorithms exist for ChIP-chip, but a rigorous assessment...
ORGANISM(S): Homo sapiens 
2008-01-31 | E-GEOD-9842 | biostudies-arrayexpress
ProteomicsPrimary human fibroblasts Proteome response to an icMERS coronavirus
Proteomics data from cell culture; time points 0, 12, 24, 36 & 48 h
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626) 
2018-01-05 | MSV000081887 | MassIVE
ProteomicsPrimary human microvascular endothelial cells Proteome response to an icMERS coronavirus
Proteomics data from cell culture; time points 0, 12, 24, 36 & 48 h
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Middle East Respiratory Syndrome-related Coronavirus (ncbitaxon:1335626) 
2018-01-05 | MSV000081888 | MassIVE
ProteomicsCalu-3 cell proteome response to H1N1 virus
Proteomics data from cell culture; Treated with wild-type H1N1 and mockulum; 5 biological replicates
ORGANISM(S): Influenza A Virus (a/wilson-smith/1933(h1n1)) (ncbitaxon:381518) Homo Sapiens (ncbitaxon:9606) 
2016-08-04 | MSV000080026 | MassIVE
ProteomicsMouse lung proteome response to a wild type infectious clone of H7N9 Influenza virus and mutants
Proteomic data from mouse lung; Treated with wild-type and mutant H7N9 and mockulum; Time points 1, 2, 4 & 7 days; 5 biological replicates
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-10-02 | MSV000079343 | MassIVE
ProteomicsMouse lymphnode proteomics response to West Nile Virus (WNV)
Proteomics data from mouse lymphnodes; Treated with wild-type and mutant WNV, and mockulum
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-08-04 | MSV000080024 | MassIVE
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