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TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 7 of 10)
Munitions constituents (MCs) including hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX), 2,4,6-trinitrotoluene (TNT), and TNT derivatives are recognized to elicit aberrant neuromuscular responses in many species. The onset of seizures resulting in death was observed in the avian model Northern bobwhite...
ORGANISM(S): Colinus virginianus 
2011-11-23 | E-GEOD-33935 | biostudies-arrayexpress
TranscriptomicsThe transcriptomes of two heritable cell types illuminate the circuit governing their differentiation
The differentiation of cells into distinct cell types, each of which is heritable for many generations, underlies many biological phenomena. White and opaque cells of the fungal pathogen Candida albicans are two such heritable cell types, each thought to be adapted to unique niches within their huma...
ORGANISM(S): Candida albicans 
2010-06-25 | E-GEOD-21291 | biostudies-arrayexpress
ProteomicsMoisture Modulates Soil Reservoirs of Active DNA and RNA viruses
Global proteomics analyses to identify viral proteins in the soil microbiome. Samples were digested with trypsin, then analyzed by LC-MS/MS. Data was searched with MS-GF+ using PNNL's DMS processing pipeline.
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
MSV000086144 | MassIVE
TranscriptomicsLKB1 modulates lung cancer differentiation and metastasis
Inherited mutation in LKB1 results in the Peutz-Jeghers syndrome (PJS), characterized by intestinal hamartomas and a modestly increased frequency of gastrointestinal and breast cancer1. Somatic inactivation of LKB1 occurs in human lung adenocarcinoma2-4, but its tumor suppressor role in this tissue ...
ORGANISM(S): Homo sapiens 
2007-08-28 | E-GEOD-6135 | biostudies-arrayexpress
TranscriptomicsTranscriptome Remodeling Associated with Chronological Aging in the Dinoflagellate, Karenia brevis
To gain an understanding of processes that underlie chronological aging in this dinoflagellate, a microarray study was carried out to identify changes in the global transcriptome that accompany the entry and maintenance of stationary phase up to the onset of cell death. The transcriptome of K. brevi...
ORGANISM(S): Karenia brevis 
2012-01-01 | E-GEOD-31913 | biostudies-arrayexpress
TranscriptomicsGSTP1 expression predicts poor pathological complete response to neoadjuvant chemotherapy in ER-negative breast cancer
The purpose of the present study was to investigate the association of glutathione S-transferase P1 (GSTP1) expression with resistance to neoadjuvant paclitaxel followed by 5-fluorouracil/epirubicin/cyclophosphamide (P-FEC) in human breast cancers. The relationship of GSTP1 expression and GSTP1 prom...
ORGANISM(S): Homo sapiens 
2012-03-20 | E-GEOD-32646 | biostudies-arrayexpress
TranscriptomicsNeurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus)
This SuperSeries is composed of the following subset Series: GSE33888: Neurotoxicogenomic investigations to assess mechanisms of action of the munitions constituents RDX and 2,6-DNT in Northern bobwhite (Colinus virginianus) (part 1 of 10) GSE33893: Neurotoxicogenomic investigations to assess mechan...
ORGANISM(S): Colinus virginianus 
2011-11-22 | E-GEOD-27653 | biostudies-arrayexpress
TranscriptomicsPlac8-dependent and iNOS-dependent T cell-mediate mechanisms clear Chlamydia muridarum infections from the genital tract
Comparison of two Chlamydia-specific CD4 T cells that are dependent on iNOS to terminate Chlamydia replication in epithelial cells to two Chlamydia-specific CD4 T cells that are iNOS-independent: Chlamydia trachomatis urogenital serovars replicate predominately in epithelial cells lining the reprod...
ORGANISM(S): Mus musculus 
2012-03-14 | E-GEOD-32128 | biostudies-arrayexpress
UnknownPredicting cognitive decline with amyloid-PET, plasma p-tau217, Aβ42/40, and p-tau217/Aβ42 in a community-based cohort - relevance for clinical trial enrollment.
Not available
S-EPMC12538628 | biostudies-literature
TranscriptomicsExpression data from Col-0 and sp1,spx2 under phosphate starvation stress and recovery after resupplying phosphate
We performed a transcriptomic analysis of Pi-starvation and recovery after resupplying Pi in Arabidopsis thaliana (Columbia-0) wild type plants and double mutant spx1,spx2. Results show that SPX1 is a Pi-dependent inhibitor of the transcription factor PHR1, a central regulatory protein in the contro...
ORGANISM(S): Arabidopsis thaliana 
2014-09-30 | E-GEOD-52046 | biostudies-arrayexpress
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