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TranscriptomicsTranscription profiling of mouse liver regeneration in Socs3 h-KO mice, Socs3 fl/fl, Alb-Cre- littermates controls
Suppressor of cytokine signaling 3 (SOCS3) down-regulates several signaling pathways in multiple cell types, and previous data suggest that SOCS3 may shut off cytokine activation at the early stages of liver regeneration. We developed hepatocyte-specific Socs3 knockout (Socs3 h-KO) mice to directly ...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9549 | biostudies-arrayexpress
TranscriptomicsChIP-chip time-course from DmD8 cells with Su(H) antibody after 0, 10, 20, 30 40, 60 and 100 minutes Notch activation
Cellular responses to signalling pathways are often highly dynamic, however most analyses of developmental signalling pathways focus on a single endpoint. We have analyzed the temporal changes in transcription following a short Notch activation treatment and related these to the recruitment of the N...
ORGANISM(S): Drosophila melanogaster 
2012-12-31 | E-GEOD-35719 | biostudies-arrayexpress
TranscriptomicsExpression profiles of Arabidopsis thaliana Col-0 seedlings and seedlings of a mutant impaired in cytoplasmic calcium elevation in response to cellotriose treatment (Johnson et al., 2017)
The endophytic fungus Piriformospora indica is a member of Sebacinales. It colonizes the roots of many plant species including the model plant Arabidospis thaliana (Peskan-Berghofer et al. 2004). P. indica promotes plant growth (Peskan-Berghofer et al. 2004), seed production (Shahollari et al. 2007)...
ORGANISM(S): Arabidopsis thaliana 
2018-02-09 | GSE98880 | GEO
TranscriptomicsThe carbonic anhydrase inhibitor ethoxzolamide inhibits the Mycobacterium tuberculosis PhoPR regulon and Esx-1 secretion and attenuates virulence
The purpose of this study was to examine how ethoxzolamide modulates gene M. tuberculosis gene expression at acidic pH. We observed that ethoxzolamide downregulates genes of the PhoPR regulon. Mtb strain CDC1551 was grown at 37C in T-25 vented, standing tissue culture flasks in 8 ml of buffered 7H9 ...
ORGANISM(S): Mycobacterium tuberculosis 
2015-05-20 | E-GEOD-63917 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila developmental time series
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
2004-11-06 | E-FLYC-6 | biostudies-arrayexpress
UnknownClinical evaluation of code-based algorithms to identify patients with pulmonary arterial hypertension in healthcare databases.
Not available
S-EPMC10851026 | biostudies-literature
UnknownRed fluorescent protein pH biosensor to detect concentrative nucleoside transport.
Not available
S-EPMC2742814 | biostudies-literature
TranscriptomicsMeasuring the effects of hypoxia on transcription in Caulobacter crescentus
To test the effects of hypoxia on transcription in Caulobacter crescentus, we cultured cells in a New Brunswick bioreactor under controlled conditions. Prior to innoculation, the medium was bubbled with laboratory air at maximum flow and stirred at 300 rpm for 2 hours. After this period, the mediu...
ORGANISM(S): Caulobacter vibrioides 
2010-06-21 | E-GEOD-21127 | biostudies-arrayexpress
TranscriptomicsTesting the effects of nitric oxide (oxidative) stress on Caulobacter transcription
The goal of this study was to measure the effects of nitric oxide exposure (using DETA NONOate as a nitric oxide donor) on transcription in Caulobacter. Untreated Caulobacter crescentus were grown to a density of 0.3 (at OD660) in PYE medium (pH 7) in rolled culture tubes. DETA-NONOate treated Cau...
ORGANISM(S): Caulobacter vibrioides 
2010-06-20 | E-GEOD-21139 | biostudies-arrayexpress
MetabolomicsMigratory Zooplankton Excreta and its Influence on Prokaryotic Communities

Particulate organic matter (fecal pellets) from zooplankton has been demonstrated to be important nutrient sources for the pelagic prokaryotic community. Significantly less is known about the chemical composition of the dissolved organic matter (DOM) produced by these eukaryotes and its infl...

2020-11-27 | MTBLS1822 | MetaboLights
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