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This project investigates how acidic pH and the bacterial endosymbiont Mycoplasma hominis influence the proteome and virulence of the human urogenital parasite Trichomonas vaginalis. Quantitative proteomic analysis was performed on T. vaginalis G3 parasites harboring M. hominis after growth for 12 d...
ORGANISM(S): Trichomonas vaginalis G3 
2026-09-14 | PXD082652 | Pride
Patients with high-grade serous ovarian cancer (HGSC) have experienced little improvement in overall survival, and standard treatment has not advanced beyond platinum-based combination chemotherapy, during the past 30 years. To understand the drivers of clinical phenotypes better, here we use whole-...
ORGANISM(S): Homo sapiens 
Ovarian cancer has a high mortality rate due, in part, to the lack of early detection and incomplete understanding of the origin of the disease. The hen is the only spontaneous model of ovarian cancer, and can therefore aid in the identification and testing of early detection strategies and therape...
ORGANISM(S): Gallus gallus 

We sequenced exomes of 94 DLBCL tumors and cell lines. 34 of the tumors had paired normal tissue. Our work elucidates commonly occurring gene-coding mutations in DLBCL.

The exit of antigen-presenting cells (APC) and lymphocytes from inflamed skin to afferent lymph is vital for the initiation and maintenance of dermal immune responses. How such exit is achieved and how cells transmigrate the distinct endothelium of lymphatic vessels is however unknown. Here we show ...
ORGANISM(S): Homo sapiens 
Background: Neuronal and glial differentiation in the murine hypothalamus is not complete at birth, but continues over the first two weeks postnatally. Nutritional status and Leptin deficiency can influence the maturation of neuronal projections and glial patterns, and hypothalamic gliosis occurs in...
ORGANISM(S): Mus musculus 
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