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ProteomicsTumour mutations in long noncoding RNAs enhance cell fitness
Tumour DNA contains thousands of somatic single nucleotide variants (SNVs) in non-protein-coding elements, yet their functional significance remains poorly understood. Amongst the most highly mutated elements are long noncoding RNAs (lncRNAs), functional transcripts with known roles in carcinogenesi...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD034007 | Pride
Driver gene  cancer  long non-coding rnas 
TranscriptomicsLong RNA Seq on Sham vs MI Adult Mouse Heart
We systematically identified, annotated and characterised the mouse long non-coding transcriptome during myocardial infarction, revealing hundreds of novel heart specific lncRNAs with unique functional and regulatory characteristics. 2 conditions, 4 biological replicates per condition
ORGANISM(S): Mus musculus 
2014-05-06 | E-GEOD-52313 | biostudies-arrayexpress
GenomicsCRISPR-Cas9 screening of lncRNAs and protein coding genes involved in the transdifferentiation from human pre-B cells into macrophages
BLaER1 cells are human leukemia pre-B cells able to transdifferentiate into functional and non-tumorigenic macrophages. With the goal of uncovering the genes involved in the transdifferentiation process, we have designed a DECKO (Double Excision CRISPR Knockout) library to knockout lncRNAs and prote...
ORGANISM(S): Homo sapiens 
2022-04-25 | E-MTAB-10445 | biostudies-arrayexpress
UnknownPrimary Palliative Care for Emergency Medicine (PRIM-ER): Protocol for a Pragmatic, Cluster-Randomised, Stepped Wedge Design to Test the Effectiveness of Primary Palliative Care Education, Training and Technical Support for Emergency Medicine.
Not available
S-EPMC6661655 | biostudies-literature
UnknownRacial, ethnic and sex-specific mechanisms of obstructive sleep apnea and Alzheimer's disease risk.
Not available
S-EPMC12835558 | biostudies-literature
GenomicsEGAS00001000374 - samples
Deep RNA sequencing in CLL
EGAD00001000258 | EGA
GenomicsU219-array-CLL-00001000374 - samples
CLL Expression Array
EGAD00010000472 | EGA
GenomicsEGAS00000000092-ega-13012012 - samples
Recurrent Somatic Mutations in CLL
EGAD00001000083 | EGA
GenomicsDeep RNA sequencing in CLL
Chronic lymphocytic leukemia (CLL) is a B-cell neoplasm with a heterogeneous clinical and biological behavior. We have performed deep RNA sequencing in different subpopulations of B-lymphocytes from healthy individuals and CLL cells from a cohort of 98 patients, and characterized the CLL transcript...
EGAS00001000374 | EGA
UnknownEmergency Nurses' Perceived Barriers and Solutions to Engaging Patients With Life-Limiting Illnesses in Serious Illness Conversations: A United States Multicenter Mixed-Method Analysis.
Not available
S-EPMC10939973 | biostudies-literature
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