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ProteomicsTRIM9 and TRIM67 interactome using the BioID approach
TRIM9 and TRIM67 are two brain enriched E3 uiquitin ligases that are critical to neuronal form and function both during embryonic development and in adult-born neurons. TRIM9 and TRIM67 interact with cytoskeletal and exocytic proteins, but the full interactome is not known.Using the BioID approach w...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-04 | PXD021758 | Pride
Embryonic cortical neurons Orbitrap fusion lumos 
TranscriptomicsTranscription profiling of rat testes following exposure to mono-(2-ethylhexyl) phthalate
In rodent models, phthalate exposure alters both the fetal and pubertal testis, but the resulting histopathological changes are divergent. This suggests that the underlying molecular and cellular phthalate mechanism may be age-dependent. Using genome-wide expression profiling of acutely-exposed ra...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-4514 | biostudies-arrayexpress
ProteomicsThe nucleosomal acidic patch relieves auto-inhibition by the ISWI remodeler SNF2h
Domain level interactions between the ISWI remodeler SNF2h and reconstituted mononucleosomes were probed by EDC crosslinking under different biochemical conditions: ADP, ADP-BeFx, ADP-BeFx with LANA peptide added (which binds at the acidic patch). A semi quantitative approach was used to monitor do...
ORGANISM(S): Xenopus Laevis (ncbitaxon:8355) Homo Sapiens (ncbitaxon:9606) 
2018-03-07 | MSV000082136 | MassIVE
TranscriptomicsTranscriptomic analysis of Sorghum bicolor responding to combined heat and drought stress
Sorghum is an important crop often subjected to simultaneous high temperatures and drought in the field. We examined the gene expression response to heat and drought stress both individually, and in combination, with the aim of identifying important stress tolerance mechanisms. Plants were subjected...
ORGANISM(S): Sorghum bicolor 
2014-06-20 | E-GEOD-48205 | biostudies-arrayexpress
GenomicsMultiple Overlapping Mammalian Chromatin Remodeling Systems Collaborate Genome-wide at Dynamic Chromatin Transitions (ChIP-Seq)
ATP-dependent chromatin remodeling is an essential process required for the dynamic organization of chromatin structure. Here we describe the genome-wide location and activity of three remodeler proteins with diverse physiological functions in the mouse genome: Brg1, Chd4, and Snf2h. The localizatio...
ORGANISM(S): Mus musculus 
2013-12-24 | E-GEOD-53583 | biostudies-arrayexpress
GenomicsMultiple Overlapping Mammalian Chromatin Remodeling Systems Collaborate Genome-wide at Dynamic Chromatin Transitions (Dnase-Seq)
ATP-dependent chromatin remodeling is an essential process required for the dynamic organization of chromatin structure. Here we describe the genome-wide location and activity of three remodeler proteins with diverse physiological functions in the mouse genome: Brg1, Chd4, and Snf2h. The localizatio...
ORGANISM(S): Mus musculus 
2013-12-24 | E-GEOD-53584 | biostudies-arrayexpress
TranscriptomicsZebrafish heart regeneration
Ischemic cardiopathy is the leading cause of death in the world, for which efficient regenerative therapy is not currently available. In mammals, after a myocardial infarction episode, the damaged myocardium is replaced by scar tissue featuring collagen deposition and tissue remodelling with negligi...
ORGANISM(S): Danio rerio 
2010-03-09 | E-GEOD-17993 | biostudies-arrayexpress
TranscriptomicsProfiling of single murine bronchioalveolar stem cells
Murine bronchioalveolar stem cells play a key role in pulmonary epithelial maintenance and repair but their molecular profile is poorly described so far. In this study, we used antibodies directed against Sca-1 and CD34, two markers originally ascribed to pulmonary cells harboring regenerative poten...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-52215 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP6.0 array for comparison of lung tumor and adjacent normal to high-throughput sequencing data
One lung tumor and its adjacent normal were profiled for copy-number alterations with the high-resolution Affymetrix SNP6.0 Array. The SRA ID for the high throughput sequencing project will accompany our study is SRP002045. One lung tumor sample and an adjacent normal sample were assayed on the Aff...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-20584 | biostudies-arrayexpress
UnknownEnhancing cognitive performance prediction by white matter hyperintensity connectivity assessment.
Not available
S-EPMC11629703 | biostudies-literature
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