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TranscriptomicsGene expression response to copper toxicity between coastal and open ocean strains of marine Synechococcus
Marine cyanobacteria are thought to be the most sensitive of the phytoplankton groups to copper toxicity, yet little is known of the transcriptional response of marine Synechococcus to copper shock. Global transcriptional response to two levels of copper shock was assayed in both a coastal and an o...
ORGANISM(S): Synechococcus sp. CC9311 
2010-05-17 | E-GEOD-13910 | biostudies-arrayexpress
MetabolomicsDelayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the infant immune system and gut microbiota occur in parallel; ...
2024-10-24 | MTBLS7919 | MetaboLights
UnknownTapered oral dexamethasone for the acute chest syndrome of sickle cell disease.
Not available
S-EPMC3368951 | biostudies-literature
TranscriptomicsRNA-seq of pancreatic CAF-derived cell line 0082T treated with Autotaxin inhibitors (IOA-289 and PF-8380) against DMSO treated controls
Autotaxin (ATX), encoded by ENPP2, catalyzes the production of lysophosphatidic acid (LPA), an important regulator within the tumor microenvironment (TME). ATX is a clinical target in pancreatic ductal adenocarcinoma (PDAC), yet the pro-tumorigenic action of the ATX/LPA axis in PDAC remains unclear....
ORGANISM(S): Homo sapiens 
2024-10-06 | E-MTAB-14494 | biostudies-arrayexpress
UnknownPlugging the leaks: antibiotic resistance at human-animal interfaces in low-resource settings.
Not available
S-EPMC10923528 | biostudies-literature
TranscriptomicsOpen Ocean and Coastal Strains of Marine Synechococcus display distinctly different Global Responses to DNA Damaging Agents
We have looked at the transcriptional response of well characterised Synechococcus open ocean (WH8102) and coastal (CC9311) isolates to two DNA damaging agents, mitomycin C and ethidium bromide, using whole genome expression microarrays. The coastal strain, which was able to grow on higher concentr...
ORGANISM(S): Synechococcus sp. WH 8102 
2013-08-01 | E-GEOD-39818 | biostudies-arrayexpress
UnknownComprehensive genomic characterization of squamous cell lung cancers.
Not available
S-EPMC3466113 | biostudies-literature
UnknownHigh-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations.
Not available
S-EPMC7002524 | biostudies-literature
UnknownScalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines.
Not available
S-EPMC6075717 | biostudies-literature
TranscriptomicsDiscovery of novel recurrent mutations and rearrangements in early T-cell precursor acute lymphoblastic leukemia by whole genome sequencing
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive malignancy of unknown genetic basis. We performed whole genome sequencing of tumour and normal DNA from 12 children with ETP ALL and assessed the frequency of somatic alterations in 52 ETP and 42 non-ETP T-ALL samples by...
ORGANISM(S): Homo sapiens 
2011-11-23 | E-GEOD-28703 | biostudies-arrayexpress
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