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TranscriptomicsDeletion of Clr3 restores expression of a subset of genes in gcn5- mutant cells
Histone acetylation and deacetylation is important for gene regulation. The histone acetyltransferase, Gcn5, is a known activator of transcriptional initiation that is recruited to gene promoters. Here we map genome-wide levels of Gcn5 occupancy and histone H3K14ac at high resolution. Gcn5 is predom...
ORGANISM(S): Schizosaccharomyces pombe 
2010-06-24 | E-GEOD-13817 | biostudies-arrayexpress
TranscriptomicsS. pombe acetyltransferase mutants identifies redundant pathways of gene regulation, dual-channel dataset
Analysis of histone acetyl transferases (HATs) from the MYST and GNAT families in S. pombe to identify functional differences or overlap with regard to gene expression. Mutations were made to Elp3 and Gcn5 (GNAT family), and to Mst2 (MYST family). Mutants showed distinct phenotypes which were repres...
ORGANISM(S): Schizosaccharomyces pombe 
2009-09-19 | E-GEOD-17259 | biostudies-arrayexpress
UnknownExpression of IFITM1 as a prognostic biomarker in resected gastric and esophageal adenocarcinoma.
Not available
S-EPMC4867989 | biostudies-literature
UnknownExpression of podocalyxin-like protein is an independent prognostic biomarker in resected esophageal and gastric adenocarcinoma.
Not available
S-EPMC4966733 | biostudies-literature
UnknownTargeting murine metastatic cancers with cholera toxin A1-adjuvanted peptide vaccines.
Not available
S-EPMC11760229 | biostudies-literature
TranscriptomicsComparison of gene regulation by Gcn5 under KCl stress in S. cerevisiae and S. pombe
This is parallel comparison of gene regulation by Gcn5 in evolutionarily divergent yeasts S. pombe and S. cerevisiae. Our study showed Gcn5 is required for a similar spectrum of stress responses in both organisms, including the response to KCl. This DNA microarray studies is to find conserved or div...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-5218 | biostudies-arrayexpress
TranscriptomicsOMalley_et_al2013
The aim of the experiment is to illuminate the molecular mechanisms of cellular reprogramming. We have isolated cells at intermediate stages of reprogramming and analysed their gene expression profiles. D6s4B5 1N- are CD44+ ICAM1-, Nanog-GFP-, D6s4B5 1N+ are CD44+ ICAM1-, Nanog-GFP+, D6s4B5 2N- are...
ORGANISM(S): Mus musculus 
2013-06-03 | E-MTAB-1654 | biostudies-arrayexpress
UnknownThe Slr protein of Streptococcus pyogenes is selectively expressed in vivo and is a target for protective antibodies
Not available
S-SCDT-10_1038-S44321-026-00470-0 | biostudies-other
TranscriptomicsReprogramming roadblocks are system-dependent
Since the first generation of induced Pluripotent Stem cells (iPSCs), several reprogramming systems have been used to study its molecular mechanisms. However, the system of choice largely affects the reprogramming efficiency, influencing our view on the mechanisms. Here we demonstrate that reprogram...
ORGANISM(S): Mus musculus 
2015-08-08 | E-GEOD-70816 | biostudies-arrayexpress
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