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TranscriptomicsMultiomic (Joint snRNA/snATAC) sequencing data of intestinal crypts and epithelial only organoids derived from human fetal duodenum
Here, we used joint single-nuclei RNA-sequencing (snRNA-seq) and single-nuclei ATAC sequencing (scATAC) to profile freshly isolated crypts from the human fetal intestine and matched intestinal epithelial only organoids (also known as enteroids) derived from these crypts after one passage of in vitro...
ORGANISM(S): Homo sapiens 
2022-07-16 | E-MTAB-11908 | biostudies-arrayexpress
TranscriptomicsOsteoarthritis-related changes in gene expression in knee articular chondrocytes in a rat model of osteoarthritis.
Cartilage destruction in osteoarthritis (OA) results from disturbed chondrocyte metabolism. Here, we used microarrays to show that TGF alpha and CCL2 are simultaneously upregulated in a rat model of OA and cooperate to drive cartilage degradation. The goals of the experiments included here were to a...
ORGANISM(S): Rattus norvegicus 
2012-11-15 | E-GEOD-42295 | biostudies-arrayexpress
TranscriptomicsMetatranscriptomes of phytoplankton blooms from an ocean acidification mesocosm experiment
Sequencing the metatranscriptome can provide information about the response of organisms to varying environmental conditions. We present a methodology for obtaining random whole-community mRNA from a complex microbial assemblage using Pyrosequencing. The metatranscriptome had, with minimum contamina...
ORGANISM(S): marine metagenome 
2008-02-08 | E-GEOD-10119 | biostudies-arrayexpress
ModelsBaker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis
Baker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis This model by Baker M. 2013, describes the interaction between pro and anti-inflammatory cytokine signalling in rheumatoid arthritis. Using two ordinary differential equations, the first model [BIOMD0000000550] analyses bifurcation...
2024-09-02 | BIOMD0000000550 | BioModels
ModelsBaker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis - Age Dependent
Baker2013 - Cytokine Mediated Inflammation in Rheumatoid Arthritis - Age Dependant This model by Baker M. 2013, describes the interaction between pro and anti-inflammatory cytokine signalling in rheumatoid arthritis. Using two ordinary differential equations, the first model [BIOMD0000000550] anal...
2024-09-02 | BIOMD0000000549 | BioModels
TranscriptomicsTranscriptomic response to substrate and temperature in two thermophilic fungi, Myceliophthora thermophila and Thielavia terrestris, and a related mesophile, Chaetomium globosum
The thermophilic filamentous fungi Myceliophthora thermophila (Sporotrichum thermophile) and Thielavia terrestris are proficient decomposers of cellulose, suggesting that they will be a rich source of thermostable industrial enzymes for lignocellulose degradation. To identify the genes and proteins...
ORGANISM(S): Myceliophthora thermophila 
2011-08-08 | E-GEOD-27323 | biostudies-arrayexpress
TranscriptomicsLinking phytoplankton community composition to seasonal changes in f ratio
Seasonal changes in nitrogen assimilation have been studied in the western English Channel by sampling at approximately weekly intervals for 12 months. Nitrate concentrations showed strong seasonal variations. Available nitrogen in the winter was dominated by nitrate but this was close to limit of d...
ORGANISM(S): synthetic construct 
2011-03-17 | E-GEOD-27998 | biostudies-arrayexpress
UnknownFibrodysplasia ossificans progressiva (FOP): A disorder of osteochondrogenesis.
Not available
S-EPMC7502483 | biostudies-literature
ModelsZhang2009 - Genome-scale metabolic network of Thermotoga maritima
Zhang2009 - Genome-scale metabolic network of Thermotoga maritima This model is described in the article: Three-dimensional structural view of the central metabolic network of Thermotoga maritima. Zhang Y, Thiele I, Weekes D, Li Z, Jaroszewski L, Ginalski K, Deacon AM, Woole...
2015-07-30 | MODEL1507180048 | BioModels
UnknownImmediate Antiretroviral Therapy Reduces Risk of Infection-Related Cancer During Early HIV Infection.
Not available
S-EPMC5146718 | biostudies-literature
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