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The intent of the study was to profile the methylome and hydroxymethylome in intestinal stem cells with young mitochondria or old old mitochdondria, to ascertain the potential role of mitochondrial age specific influence on epigenetic regulation of ISCs.
ORGANISM(S): Mus musculus 
The object of this study was to investigate how aKG impacts mouse intestinal stem cell (ISCs) function and fate decisions in vivo. Mice were treated for 7 days with twice daily aKG IP injections after which ISCs were FACS sorted and transcriptomically anayzled. This revealed a striking set of secret...
ORGANISM(S): Mus musculus 
Comparison of the expression profiles of nac45-2 nac86 mutant with col WT, and comparison of the expression profiles of NAC45 extopical induction with non-induction. Three-dye gene expression study with three biological replicates. Five-point time-series experiment and double-mutant vs wild-type com...
ORGANISM(S): Arabidopsis thaliana 
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