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MetabolomicsMetabolic Profiling of Volatile Organic Compounds (VOCs) Emitted by the Pathogens Francisella tularensis and Bacillus anthracis in Liquid Culture
We conducted comprehensive (untargeted) metabolic profiling of volatile organic compounds (VOCs) emitted in culture by bacterial taxa Francisella tularensis (F. tularensis) subspecies novicida and Bacillus anthracis (B. anthracis) Sterne, surrogates for potential bacterial bioterrorism agents, as we...
2020-08-20 | MTBLS1737 | MetaboLights
ProteomicsSearch for synaptic biomarkers of Alzheimer’s disease
As synapse degeneration is an early event in Alzheimer’s disease (AD) pathophysiology, a biofluid marker of synapse loss in living patients could be a surrogate marker of disease prognosis and therefore would be an excellent addition to the AD biomarker arsenal. With direct access to the brain inter...
ORGANISM(S): Homo Sapiens 
2019-01-10 | PXD012138 | panorama
TranscriptomicsEXPRSS: an Illumina based high-throughput expression-profiling method to reveal transcriptional dynamics - III
Background Next Generation Sequencing technologies have facilitated differential gene expression analysis through RNA-seq and Tag-seq methods. RNA-seq has biases associated with transcript lengths, lacks uniform coverage of regions in mRNA and requires 10M-bM-^@M-^S20 times more reads than a typical...
ORGANISM(S): Arabidopsis thaliana 
2014-06-20 | E-GEOD-52596 | biostudies-arrayexpress
MetabolomicsTargeted metabolomic analysis in hepatic extracts, serum, and urine of female mice gavaged with TCDD every 4 days for 28 days
TCDD is an environmental contaminant that elicits a number of hepatic effects including fat accumulation, inflammation, and fibrosis that can progress to hepatocellular carcinoma. RNA-Seq and targeted metabolomics were integrated with complementary dioxin response element (DRE) location and aryl hyd...
2017-02-02 | MTBLS225 | MetaboLights
TranscriptomicsThe transcriptional repressor BLIMP1 curbs host-defenses by suppressing expression of the chemokine CCL8
The transcriptional repressor BLIMP1 is a master regulator of B and T cell differentiation. To examine the role of BLIMP1 in innate immunity we used a conditional knockout (CKO) of Blimp1 in myeloid cells and found that Blimp1 CKO mice were protected from lethal infection induced by Listeria monocyt...
ORGANISM(S): Mus musculus 
2013-12-10 | E-GEOD-53145 | biostudies-arrayexpress
ProteomicsGeotraces EPZT
Surface seawater ENV solid phase extraction samples collected on the US GEOTRACES EPZT cruise (October-December 2013).
ORGANISM(S): Environmental Samples <bacillariophyta> (ncbitaxon:33858) 
MSV000080173 | MassIVE
UnknownA 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity.
Not available
S-EPMC4841173 | biostudies-literature
UnknownDesign and conduct of the CALERIE study: comprehensive assessment of the long-term effects of reducing intake of energy.
Not available
S-EPMC3032519 | biostudies-literature
UnknownDevelopment and application of quality assurance methods for interventions in randomised controlled trials of surgical oncology: the ROMIO study (a comparison of minimally invasive and open oesophagectomy).
Not available
S-EPMC12852800 | biostudies-literature
UnknownCross-species consensus atlas of the primate basal ganglia.
Not available
S-EPMC12724601 | biostudies-literature
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