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MetabolomicsDiel metabolomics analysis of a hot spring chlorophototrophic microbial mat leads to new hypotheses of community member metabolisms
Dynamic environmental factors such as light, nutrients, salt, and temperature continuously affect chlorophototrophic microbial mats, requiring adaptive and acclimative responses to stabilize composition and function. Quantitative metabolomics analysis can provide insights into metabolite dynamics fo...
2024-02-23 | MTBLS187 | MetaboLights
TranscriptomicsRNA-seq of isolated human foetal and hiPSC L/M-opsin cone photoreceptor populations labelled using the AAV2/9.pR2.1.GFP reporter
The loss of cone photoreceptor cells, which are critical for optimal daylight vision, have the great impact on vision during retinal degenerations. Retinal differentiation of human induced pluripotent stem cell (hiPSC) sources could provide a renewable source of cone photoreceptors towards developin...
ORGANISM(S): Homo sapiens 
2018-04-20 | E-MTAB-6057 | biostudies-arrayexpress
UnknownPhylogenomics and genetic analysis of solvent-producing Clostridium species.
Not available
S-EPMC11063209 | biostudies-literature
TranscriptomicsOligoarray comparative genomic hybridisation-mediated mapping of suppressors of an essential receptor tyrosine kinase generated in a deletion-biased mutagenesis screen
We have used oligoarray comparative genomic hybridization (aCGH) to identify novel suppressors generated in a UV-TMP based suppressor screen. This approach is suitable for detecting single gene mutations as well as copy number variations. Keywords: C.elegans Suppressor screen array CGH [1] 2 test s...
ORGANISM(S): Caenorhabditis elegans 
2012-07-12 | E-GEOD-15224 | biostudies-arrayexpress
MetabolomicsTranscript, protein and metabolite temporal dynamics in the CAM plant Agave
Already a proven mechanism for drought sustainability, crassulacean acid metabolism (CAM) is a specialized type of photosynthesis that maximizes water-use efficiency (WUE) via an inverse (compared to C3 and C4 photosynthesis-performing species) day/night pattern of stomatal closure/opening to shift ...
2017-10-13 | MTBLS363 | MetaboLights
UnknownNeural Processing and Perceived Discrimination Stress in African Americans.
Not available
S-EPMC7483233 | biostudies-literature
TranscriptomicsSingle cell RNA-seq of isolated human foetal L/M-opsin cone photoreceptor populations labelled using the AAV2/9.pR2.1.GFP reporter
Human cone photoreceptors represent a rare cell population of the human retina and are largely outnumbered by other retinal cell types. Despite their rarity, cone photoreceptors are critical for optimal daylight vision and their loss has the greatest impact on sight during the progression of retinal...
ORGANISM(S): Homo sapiens 
2018-04-20 | E-MTAB-6058 | biostudies-arrayexpress
TranscriptomicsThe impact of experience-dependent and independent factors on gene expression in songbird brain [e08]
Songbirds provide rich natural models for studying the relationships of brain anatomy, behavioral function, environmental signals and gene expression. Under the Songbird Neurogenomics Initiative, investigators from more than a dozen laboratories collected brain samples from six species of songbird ...
ORGANISM(S): Sturnus vulgaris 
2012-05-30 | E-GEOD-36734 | biostudies-arrayexpress
TranscriptomicsArray-based comparative genomic hybridisation analysis at 1Mb resolution of 44 pilocytic astrocytomas
Pilocytic astrocytomas (PAs), WHO Grade I, are one of the most frequently occurring childhood brain tumors. We have used microarray comparative genomic hybridization (aCGH) at 1Mb resolution to study copy number changes in a series of PAs (n=44). Single hybridization per case. 44 pilocytic astrocyto...
ORGANISM(S): Homo sapiens 
2008-04-28 | E-GEOD-11263 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma (PDAC)
Determine methylation pattern in PDAC a genome-wide analysis was performed in a cohort of 167 PDAC and 29 adjacent pancreatic tissues samples using the Infinium 450k methylation arrays (Illumina). 167 pancreatic tumors (PDAC) x 29 adjacent -non tumor samples.
ORGANISM(S): Homo sapiens 
2014-07-08 | E-GEOD-49149 | biostudies-arrayexpress
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