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TranscriptomicsApplication of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using a novel e-cigarette device with MESH(TM) technology (microRNA data)
We previously put forward a multi-layer systems toxicology framework for in vitro assessment of e-liquids that is meant to complement the battery of classical assays for genotoxicity testing. The framework started with the first layer to screen e-liquids for their potential toxicity, followed by the...
ORGANISM(S): Homo sapiens 
2019-11-01 | E-MTAB-7912 | biostudies-arrayexpress
TranscriptomicsApplication of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using a novel e-cigarette device with MESH(TM) technology (mRNA data)
We previously put forward a multi-layer systems toxicology framework for in vitro assessment of e-liquids that is meant to complement the battery of classical assays for genotoxicity testing. The framework started with the first layer to screen e-liquids for their potential toxicity, followed by the...
ORGANISM(S): Homo sapiens 
2019-11-01 | E-MTAB-7911 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of esg+-midgut progenitor cells expressing esgRNAi or UAS-esg AND of whole midgut tissue from flies overexpressing UAS-esg in enterocyte (EC) cells
RNA-Seq of amplified mRNA from sorted esg+-midgut progenitor cells expressing esgRNAi or UAS-esg AND RNA-Seq of whole midgut tissue from flies overexpressing UAS-esg and UAS-esg+UAS-dIAP (+control empty vector RNAi, UAS-dIAP and w1118) using the MyoIA-Gal4ts EC-driver
ORGANISM(S): Drosophila melanogaster 
2014-10-25 | E-MTAB-2915 | biostudies-arrayexpress
TranscriptomicsTransforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells
Exon-level transcriptome analysis of embryonal carcinoma (EC) and embryonic stem (ES) cell lines. To circumvent difficulties of isolating pure populations of cancer stem cells for the purpose of identifying malignancy-specific gene expression, we have compared exon-resolution transcriptomic profiles...
ORGANISM(S): Homo sapiens 
2015-01-01 | E-GEOD-34855 | biostudies-arrayexpress
TranscriptomicsTranscriptomes of isolated rice gametes characterized by deep sequencing: Evidence for distinct sex-dependent chromatin and epigenetic states before fertilization
The formation of a zygote by the fusion of egg and sperm involves the two gametic transcriptomes. In flowering plants, the embryo sac embedded within the ovule contains the egg cell, while the pollen grain contains two sperm cells inside a supporting vegetative cell. The difficulties of collecting ...
ORGANISM(S): Oryza sativa Japonica Group 
2013-10-31 | E-GEOD-50777 | biostudies-arrayexpress
UnknownThe paradox of NKp46+ natural killer cells: drivers of severe hepatitis C virus-induced pathology but in-vivo resistance to interferon α treatment.
Not available
S-EPMC3932740 | biostudies-literature
UnknownIn silico description of the adsorption of cell signaling pathway proteins ovalbumin, glutathione, LC3, TLR4, ASC PYCARD, PI3K and NF-Kβ on 7.0 nm gold nanoparticles: obtaining their Lennard-Jones-like potentials through docking and molecular mechanics.
Not available
S-EPMC10697183 | biostudies-literature
TranscriptomicsScreening and validation of lncRNAs and circRNAs as miRNA sponges [cell lines, miRNA-2_0]
Intensive research in past two decades has uncovered the presence and importance of noncoding RNAs (ncRNAs), which includes microRNAs (miRs) and long ncRNAs (lncRNAs). These two classes of ncRNAs interact to a certain extent, as some lncRNAs bind to miRs to sequester them. Such lncRNAs are collectiv...
ORGANISM(S): Homo sapiens 
2016-07-06 | E-GEOD-73690 | biostudies-arrayexpress
UnknownEarly-middle Permian Mediterranean gorgonopsian suggests an equatorial origin of therapsids.
Not available
S-EPMC11652623 | biostudies-literature
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
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