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MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
UnknownKetamine Blocks Morphine-Induced Conditioned Place Preference and Anxiety-Like Behaviors in Mice.
Not available
S-EPMC7253643 | biostudies-literature
UnknownPhase variation of a signal transduction system controls Clostridioides difficile colony morphology, motility, and virulence.
Not available
S-EPMC6837544 | biostudies-literature
UnknownMatricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction.
Not available
S-EPMC11476287 | biostudies-literature
UnknownRandomised, placebo-controlled, phase 3 trial of the effect of the omega-3 polyunsaturated fatty acid eicosapentaenoic acid (EPA) on colorectal cancer recurrence and survival after surgery for resectable liver metastases: EPA for Metastasis Trial 2 (EMT2) study protocol.
Not available
S-EPMC10689403 | biostudies-literature
UnknownEffect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study.
Not available
S-EPMC7116538 | biostudies-literature
UnknownADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection.
Not available
S-EPMC8598021 | biostudies-literature
UnknownAge-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.
Not available
S-EPMC2847747 | biostudies-literature
UnknownVaccine Efficacy of ALVAC-HIV and Bivalent Subtype C gp120-MF59 in Adults.
Not available
S-EPMC7888373 | biostudies-literature
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