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TranscriptomicsTranscription profiling of E. coli K-12 W3110 strain grown at Ph5.7, 7.0, 8.5 reveals pH and anaerobiosis coregulate metabolism, multidrug transporters, and envelope composition
In Escherichia coli, pH-dependent gene expression varies with oxygen level. Anaerobic pH-dependent expression ratios were analyzed and compared to the published analysis of aerated cultures (Maurer et al, 2005). E. coli K-12 strain W3110 was cultured in closed tubes containing LBK broth buffered a...
ORGANISM(S): Escherichia coli 
2008-06-13 | E-GEOD-4556 | biostudies-arrayexpress
GenomicsPCGP Ph-likeALL WES - samples
DATA FILES FOR Ph-likeALL WES
EGAD00001001054 | EGA
GenomicsPCGP Ph-like ALL
Background: BCR-ABL1-like, or Ph-like acute lymphoblastic leukemia is characterized by a gene expression profile similar to BCR-ABL1 positive ALL, genetic alterations of lymphoid transcription factor genes, and poor outcome. Sequencing of small numbers of Ph-like ALL cases has identified genetic alt...
EGAS00001000654 | EGA
TranscriptomicsBase and acid resistance of B. subtilis associated with transcriptomic responses
Gene expression profiles of Bacillus subtilis strain AG174 were compared as a function of steady-state external pH during growth with aeration. Aerated overnight cultures were diluted 1:500 and incubated in 250 mL baffled flasks containing potassium-modified Luria-Bertani medium (LBK) buffered with ...
ORGANISM(S): Bacillus subtilis 
2009-01-12 | E-GEOD-11810 | biostudies-arrayexpress
GenomicsPCGP Ph-likeALL SNP6 - samples
PCGP Ph-likeALL SNP6
EGAD00010000598 | EGA
GenomicsPCGP Ph-likeALL GEA - samples
PCGP Ph-likeALL GEA
EGAD00010000596 | EGA
ProteomicsStructure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism
Rho GTPases regulate actin dynamics and cell motility, and their hyperactivation drives cancer metastasis1. P-Rex (PI(3,4,5)P3-dependent Rac Exchanger) guanine nucleotide exchange factors (GEFs) are potent on-switches for Rho GTPase signalling and are frequently dysregulated in metastatic cancer2. P...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD034327 | Pride
Cancer Rac1 Cryo-em P-rex1 Metastasis 
UnknownDistinct moieties underlie biphasic H+ gating of connexin43 channels, producing a pH optimum for intercellular communication.
Not available
S-EPMC5893178 | biostudies-literature
UnknownWeak temperature dependence of P (+) H A (-) recombination in mutant Rhodobacter sphaeroides reaction centers.
Not available
S-EPMC4877430 | biostudies-literature
ProteomicsComparative genomic, proteomic and exoproteomic analyses of three Pseudomonas spp.
Bacteria that inhabit the rhizosphere of agricultural crops can have a beneficial effect on crop growth, including through the solubilisation and remineralisation of complex forms of phosphorus (P). However[1], our understanding of the bacterial proteomic response to P stress is limited. Here, ex...
ORGANISM(S): Pseudomonas putida (strain BIRD-1) 
2016-08-22 | PXD003731 | Pride
Exoproteome p. bird 
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