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To determine the downstream molecular mechanism of PRLX-93936, we performed systematic proteomic profiling of cells treated with PRLX-93936, erastin, or JWZ-8-103. Results include global proteome profiling, ubiquitylation proteomics, and proximity labeling proteomics enabling comparison of drug-indu...
ORGANISM(S): Homo sapiens (Human) 
2025-08-15 | PXD059137 | Pride
Sequence data from two medullary thyroid carcinoma patients: WGS datasets generated from tumors and matched normal tissues and RNA-Seq from tumors are included.
Medullary thyroid cancer is the neoplasm of the calcitonin-producing parafollicular cells of the thyroid gland. The hormone calcitonin acts to lower the blood calcium level, counteracting the effects of the parathyroid hormone; it can also serve as a biomarker for the presence or recurrence of medul...
This dataset includes WGS & WTS alignment data generated from 1 ATC tumor, its matched peripheral blood specimen and 3 authenticated ATC cell lines, THJ-16T, THJ-21T and THJ-29T. In addition, it includes WTS data from extra 4 unique anaplastic cell lines, ACT-1, C643, HTh7 and T238.
Whole genome and transcriptome analysis of anaplastic thyroid carcinoma
RNA sequencing data for 170 medulloblastoma tumor samples
WGS data of medulloblastoma tumor/control pairs.
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